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ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >Cytidine

Cytidine

Cytidine Structure
CAS No.
65-46-3
Chemical Name:
Cytidine
Synonyms
4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one;Cyd;Citydine;Cytosine β-D-riboside;Cytosine β-D-riboside;Citidine;Cytidin;Cytidine;Cytinide;Cytidylic
CBNumber:
CB7854079
Molecular Formula:
C9H13N3O5
Molecular Weight:
243.22
MOL File:
65-46-3.mol
MSDS File:
SDS
Modify Date:
2024/4/24 17:21:45
Request For Quotation

Cytidine Properties

Melting point 210-220 °C (dec.) (lit.)
Boiling point 386.09°C (rough estimate)
alpha 31.5 º (c=0.6, H2O 25 ºC)
Density 1.3686 (rough estimate)
refractive index 34 ° (C=0.7, H2O)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
pka 4.22, 12.5(at 25℃)
form powder
color White to almost white
optical activity [α]20/D +33°, c = 2 in H2O
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,2786
BRN 89173
Stability Stable. Incompatible with strong oxidizing agents. Protect from moisture.
LogP -1.808 (est)
CAS DataBase Reference 65-46-3(CAS DataBase Reference)
NIST Chemistry Reference Cytidine(65-46-3)
EPA Substance Registry System Cytidine (65-46-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Risk Statements  68
Safety Statements  24/25
WGK Germany  3
RTECS  UW7370000
F  10-23
TSCA  Yes
HS Code  29349990
Toxicity LD50 intraperitoneal in mouse: 2700mg/kg
NFPA 704
1
0 1

Cytidine price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C4654 Cytidine BioReagent, suitable for cell culture, powder, ≥99% 65-46-3 1G ₹4113.5 2022-06-14 Buy
Sigma-Aldrich(India) C4654 Cytidine BioReagent, suitable for cell culture, powder, ≥99% 65-46-3 5G ₹8421.85 2022-06-14 Buy
Sigma-Aldrich(India) C4654 Cytidine BioReagent, suitable for cell culture, powder, ≥99% 65-46-3 50G ₹50855.85 2022-06-14 Buy
Sigma-Aldrich(India) C122106 Cytidine 99% 65-46-3 1G ₹2760.38 2022-06-14 Buy
Sigma-Aldrich(India) C122106 Cytidine 99% 65-46-3 10G ₹4405.78 2022-06-14 Buy
Product number Packaging Price Buy
C4654 1G ₹4113.5 Buy
C4654 5G ₹8421.85 Buy
C4654 50G ₹50855.85 Buy
C122106 1G ₹2760.38 Buy
C122106 10G ₹4405.78 Buy

Cytidine Chemical Properties,Uses,Production

Description

Cytidine is a pyrimidine nucleoside that is composed of the pyrimidine base cytosine attached to the sugar ribose. As a constituent of RNA, cytidine pairs with guanine, and it is a precursor of uridine. Cytidine can incur several modifications in mRNA, including methylation and acetylation, that function to regulate translation. Cytidine can also be formylated to 5-formylcytidine in mitochondrial methionine transfer RNA (tRNAMet).

Chemical Properties

Cytidine is a component of RNA. It is a white water-soluble solid. which is only slightly soluble in ethanol.There are a variety of cytidine analogs with potentially useful pharmacology.

Uses

Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. It was isolated from yeast nucleic acid. It can increases cell membrane phospholipids. Cytidine is used to synthesize enzyme inhibitors, antiviral agents, and anticancer agents. And also used as constituent of nucleic acids.

Definition

ChEBI: cytidine is a pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It derives from a cytosine.The derivednucleotides, cytidine mono-, di-, andtriphosphate (CMP, CDP, and CTP respectively)participate in various biochemicalreactions, notably inphospholipid synthesis.

Application

Cytidine has been used as a non-essential aminoacid component of minimal essential medium (MEM) to analyse interspecies somatic cell nucleus transfer (iSCNT)-derived blastocysts. It has also been used as a supplement in the culture medium of HeLa cells, to study the effects of cytidine addition on rods and rings (RR) induced by glutamine deprivation.
Cytidine has been used as a component to prepare ribonucleoside stock solution to assess its effects on the anaerobic growth of several Bacillus mojavensis strains.

General Description

White crystalline powder.

Air & Water Reactions

Cytidine is hygroscopic. Water soluble.

Reactivity Profile

Cytidine is incompatible with strong oxidizing agents. . Will react as a weak base.

Fire Hazard

Flash point data for Cytidine are not available; however, Cytidine is probably combustible.

Purification Methods

Cytidine crystallises from 90% aqueous EtOH. It has also been converted to sulfate by dissolving (~200mg) in a solution of EtOH (10mL) containing H2SO4 (50mg), whereby the salt crystallises out. It is collected, washed with EtOH and dried for 5hours at 120o/0.1mm. The sulfate has m 225o. The free base is obtained by shaking the salt solution with a weak ion-exchange resin, filtering, evaporating and recrystallising the residue from EtOH as before. [Fox & Goodman J Am Chem Soc 73 3256 1956, Fox & Shugar Biochim Biophys Acta 9 369 1952; see Prytsas & Sorm in Synthetic Procedures in Nucleic Acid Chemistry (Zorbach & Tipson Eds) Vol 1 404 1973.] [Beilstein 25 III/IV 3667.]

Cytidine Preparation Products And Raw materials

Raw materials

Preparation Products

1-beta-D-Arabinofuranosylcytosine hydrochloride Zalcitabine Calcium 5'-ribonucleotide N4-Benzoylcytidine CYTIDINE 3'-MONOPHOSPHATE
3-METHYL URIDINE 5-Iodocytidine N4-Acetylcytidine (+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine
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Cytidine Suppliers

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SYNOVA CHEMICALS +91-9920741772 +91-9920741772 Mumbai, India 428 58 Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
Arown Pharma +91-914040277600 +91-8309108338 Hyderabad, India 46 58 Inquiry
Vidgas science and technologies Pvt Ltd +91-9030019844 +91-9030019844 Telangana, India 76 58 Inquiry
Sintilla Medcoms Pvt Ltd +91-4027808001 +91-8886733867 Telangana, India 307 58 Inquiry
Meteoric Biopharmaceuticals Pvt. Ltd. +91-8511121361 +91-8511121361 Mumbai, India 71 58 Inquiry
CHEMYZOLAB +91-7276286755 +91-9558347707 Karnataka, India 1 58 Inquiry
S D Fine Chem Limited +91-9323715856 +91-9323715856 Maharashtra, India 368 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Supplier Advantage
SYNOVA CHEMICALS 58
GLP Pharma Standards 58
Arown Pharma 58
Vidgas science and technologies Pvt Ltd 58
Sintilla Medcoms Pvt Ltd 58
Meteoric Biopharmaceuticals Pvt. Ltd. 58
CHEMYZOLAB 58
S D Fine Chem Limited 58
TCI Chemicals (India) Pvt. Ltd. 58
A.J Chemicals 58

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Cytidine Spectrum

Cytidine(65-46-3)MSCytidine(65-46-3)1HNMRCytidine(65-46-3)13CNMRCytidine(65-46-3)IR1Cytidine(65-46-3)IR2Cytidine(65-46-3)Raman

65-46-3(Cytidine)Related Search:

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2'-Deoxycytidine-5'-monophosphoric acid CYTIDYLYL-(3'->5')-GUANOSINE 3-METHYLCYTIDINE METHOSULFATE
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Cytidine,Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside Cytidine, 99+% 10GR Cytidine, 99+% 50GR 1-β-D-ribosylcytosine Cytidin Cytosine, 1-beta-D-ribofuranosyl- CYTIDINE HYDROCHLORIDE Cytidine, 99.5% 4-AMINO-1-BETA-D-RIBOFLURANOSYL-2-PYRIMIDINONE 1-β-D-Ribofuranosylcytosin 1-beta-D-Ribofuranosyl cytidine(CR) 1-beta-Ribofuranosylosine 4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone Cytidine, 97+% Cytidylic 1-(β-D-Ribofuranosyl)cytosine 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone 5-(β-D-Ribofuranosyl)cytosine Pseudocytidine CYTIDINE FREE BASE CELL CULTURE TESTED Cytosine-1-β-D-ribofuranos CytidineForBiochemistry Cytidene,>98% 4-Amino-L-β-D-ribofuranosyl-2-[1H]-pyrimidinone Cytidine, 99+% CYTIDINE(Cytosine-1--D-ribofuranoside) CYTIDINE,FREEBASE,HIGHPURITY 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-pyrimidin-2-one CYTARABINEHYDROCHLORIDE CYTIDINE (CYTOSINE RIBOSIDE) CYTIDINE extrapure Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside 1-b-Ribofuranosylcytosine 2(1H)-Pyrimidinone, 4-amino-1-b-D-ribofuranosyl- 1beta-D-Ribofuranosylcytosine 1-beta-ribofuranosylcytosine 1beta-Ribofuranosylcytosine 2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl- 4-amino-1-beta-d-ribofuranosyl-2(1h)-pyrimidinon beta-D-Ribofuranoside, cytosine-1 Cytidine DEOXYCHOLIC ACID NA SALT HIGH PURITY ara-L-cytidine Citicoline, CDPC, Nicholin, Audes Diquafosol Impurity 16 Cytidine > Cytidine Powder Cytidine USP/EP/BP 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone Professional Manufacturer CAS?65-46-3?Cytidine Powder Cytosine-1-β-D-ribofuranoside Cytidine for biochemistry 1GM Cytidine for biochemistry 5GM Cytidine for biochemistry 25GM Cytinide 4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one Cytosine β-D-riboside Cyd