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ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleoside Intermediates >N4-Acetylcytidine

N4-Acetylcytidine

N4-Acetylcytidine Structure
CAS No.
3768-18-1
Chemical Name:
N4-Acetylcytidine
Synonyms
N-Acetylcytidine;Ac-rC;Acetylcytidine;rC(Ac);N4-Ac-Cr;N4-Ac-rC;ACETYL CYTOSINE;n-acetyl-cytidin;4-Acetylcytidine;N4-ACETYLCYTIDINE
CBNumber:
CB1207392
Molecular Formula:
C11H15N3O6
Molecular Weight:
285.25
MOL File:
3768-18-1.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00
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N4-Acetylcytidine Properties

Melting point 199 °C (dec.)(lit.)
Density 1.72±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka 10.21±0.20(Predicted)
form Solid
color White to Pale Yellow
CAS DataBase Reference 3768-18-1(CAS DataBase Reference)
NIST Chemistry Reference Cytidine, n-acetyl-(3768-18-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  36-36/37/39-26
WGK Germany  3
HS Code  29335990
NFPA 704
0
3 0

N4-Acetylcytidine Chemical Properties,Uses,Production

Description

N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. tRNA has been shown to be excreted in abnormal amounts in the urine of cancer patients. tRNA from neoplastic tissue had a much more rapid turnover rate than the tRNA from the corresponding normal tissue. Evidence indicates that methylation of tRNA occurs only after synthesis of the intact macromolecule. Because there are no specific enzyme systems to incorporate the modified nucleosides into the macromolecular nucleic acid, these nucleosides once released in the process of tRNA turnover cannot be reutilized, nor are they further degraded, but are excreted in urine.
N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.

Uses

N4-Acetylcytidine (cas# 3768-18-1) is a nucleotide-derived metabolite used as biomarkers for diagnosis of inflammation-related diseases.

Definition

ChEBI: N(4)-acetylcytidine is cytidine in which one of the exocyclic amino hydrogens is substituted by an acetyl group. It has a role as a metabolite. It is a member of cytidines, a member of acetamides and a secondary carboxamide.

N4-Acetylcytidine Preparation Products And Raw materials

Raw materials

N-Acetyl-2'-O,3'-O,5'-O-triacetylcytidine Acetyl chloride Cytidine Acetic anhydride Acetic acid

Preparation Products

Zalcitabine

N4-Acetylcytidine Suppliers

Global( 212)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Vagmine Bio 08068970605Ext 713 Hyderabad, India 13 58 Inquiry
Zhejiang Hengkang Pharmaceutical Co., Ltd. +86-576-83372028 +86-18868723926 China 119 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16209 58 Inquiry
Shanghai Bojing Chemical Co.,Ltd. +86-86-02137122233 +8613795318958 China 299 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7353 58 Inquiry
Xiamen AmoyChem Co., Ltd +86-592-6051114 +8618959220845 China 6387 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Vagmine Bio 58
Zhejiang Hengkang Pharmaceutical Co., Ltd. 58
Shanghai Daken Advanced Materials Co.,Ltd 58
Shanghai Bojing Chemical Co.,Ltd. 55
career henan chemical co 58
Jinan Carbotang Biotech Co.,Ltd. 58
Xiamen AmoyChem Co., Ltd 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58

N4-Acetylcytidine Spectrum

N4-Acetylcytidine(3768-18-1)MSN4-Acetylcytidine(3768-18-1)1HNMRN4-Acetylcytidine(3768-18-1)IR1N4-Acetylcytidine(3768-18-1)IR2

3768-18-1(N4-Acetylcytidine)Related Search:

Fluorocytosine 1-(5-Pyrimidinyl)ethanone Acetylcholine Acetaminophen Acetyl chloride
Isocytosine Cytosine Acetylacetone Acetylspiramycin N4-Benzoylcytidine
2-Methyl-4-amino-5-acetylaminomethyl pyrimidine N4-Acetylcytosine N4-BENZOYL-2'-O-METHYLCYTIDINE 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-[[4-(tert-butyl)phenoxy]acetyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite N4-BENZOYL-5'-O-DMT-CYTIDINE
Cytidine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-ACETYL-5'-(DIMETHOXYTRITYL)-2'-O-METHYLCYTIDINE
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4-Acetyl-1-(beta-D-ribofuranosyl)cytosine ACETYL CYTOSINE N4-ACETYLCYTIDINE 4-Acetylcytidine Acetamide, N-(1,2-dihydro-2-oxo-1-beta-D-ribofuranosyl-4-pyrimidinyl)- n-acetyl-cytidin N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-pyrimidin-4-yl]ethanamide N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2-keto-pyrimidin-4-yl]acetamide N4-Acetyl-D-cytidine N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide N4 CACETYLCYTIDINE N(sup 4)-acetylcytidine N4-Acetylcytidine N4-Ac-Cr N4-Ac-rC N4-Acetylcytidine, 97.5% N4-Acetylcytidine, 97.5% Cytidine, N-acetyl- N4-Acetylcytidine USP/EP/BP Acetylcytidine N-Acetylcytidine Ac-rC N4-Acetyl cytidine,RNA modified nucleoside ac4C RNA modified nucleoside ac4C Cytidine Impurity 1 (N4-Acetylcytidine) rC(Ac) 3768-18-1 C11H15N3O6 Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents BioChemical Biochemicals and Reagents Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Nucleic acids Modified（deoxy）nucleoside