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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >Thymine

Thymine

Thymine Structure
CAS No.
65-71-4
Chemical Name:
Thymine
Synonyms
5-Methylpyrimidine-2,4(1H,3H)-dione;THYMIN;5-METHYLURACIL;5-Methyl-2,4-dioxypyrimidine;Zidovudine Related CoMpound C;2,4-DIHYDROXY-5-METHYLPYRIMIDINE;5-Methyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 5-methyl-;hymine;THYMINE
CBNumber:
CB8854081
Molecular Formula:
C5H6N2O2
Molecular Weight:
126.11
MOL File:
65-71-4.mol
MSDS File:
SDS
Modify Date:
2024/5/11 9:14:28
Request For Quotation

Thymine Properties

Melting point ~320 °C (dec.) (lit.)
Boiling point 234.21°C (rough estimate)
Density 1.3541 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Powder
pka 9.94(at 25℃)
color White
Water Solubility Soluble in hot water. Slightly soluble in alcohol.
Decomposition 335 °C
Merck 14,9398
BRN 607626
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey RWQNBRDOKXIBIV-UHFFFAOYSA-N
LogP -0.620
CAS DataBase Reference 65-71-4(CAS DataBase Reference)
NIST Chemistry Reference Thymine(65-71-4)
EPA Substance Registry System Thymine (65-71-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  22-24/25-37/39-26
WGK Germany  2
RTECS  XP2100000
TSCA  Yes
HS Code  29335990
NFPA 704
1
2 0

Thymine price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T0895 Thymine suitable for cell culture, BioReagent 65-71-4 5G ₹3030.3 2022-06-14 Buy
Sigma-Aldrich(India) T0376 Thymine ≥99% 65-71-4 10G ₹3885 2022-06-14 Buy
Sigma-Aldrich(India) T0376 Thymine ≥99% 65-71-4 25G ₹3918.3 2022-06-14 Buy
Sigma-Aldrich(India) T0895 Thymine suitable for cell culture, BioReagent 65-71-4 25G ₹8979.9 2022-06-14 Buy
Sigma-Aldrich(India) T0376 Thymine ≥99% 65-71-4 5G ₹5083.8 2022-06-14 Buy
Product number Packaging Price Buy
T0895 5G ₹3030.3 Buy
T0376 10G ₹3885 Buy
T0376 25G ₹3918.3 Buy
T0895 25G ₹8979.9 Buy
T0376 5G ₹5083.8 Buy

Thymine Chemical Properties,Uses,Production

Chemical Properties

White, crystalline powder. Slightly soluble in hot water; insoluble in coldwater, alcohol; sparingly soluble in ether; readily soluble in alkalies.

Uses

Thymine is a nitrogenous base component in the nucleic acid of DNA.

Definition

thymine: A pyrimidine derivativeand one of the major componentbases of nucleotides and the nucleicacid DNA.

General Description

Thymine (Zidovudine Related Compound C) is a process related impurity of antiretroviral drug zidovudine. Zidovudine belongs to the class of drugs known as nucleoside reverse transcriptase inhibitors and is generally used in the prevention and treatment of HIV/AIDS.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Crystallise thymine from EtOAc, 10% aqueous EtOH or water. It has m 318-320o after sublimation at 200o/12mm. Purify it by preparative (2mm thick) TLC plates of silica gel, eluting with ethyl acetate/isopropanol/water (75:16:9, v/v; RF 0.75). The desired spot is localated with a uv lamp, cut the band from the plate, place it in MeOH, shake and filter it through a millipore filter, then evaporate. [Infante et al. J Chem Soc, Faraday Trans 1 68 1586 1973, Beilstein 24 H 353, 24 I 330, 24 II 183, 24 III/IV 1292.]

Thymine Preparation Products And Raw materials

Raw materials

Ethanol Urea Butyl acetate Hydrochloric acid Acetic acid
Methanol Methyl methacrylate 1-(2-Deoxy-β-D-ribopyranosyl)thymine 5-METHYLCYTOSINE 4(1H)-Pyrimidinone, 2-amino-5-methyl- (7CI,8CI,9CI)
2'-O-(2-Methoxyethyl)-5-methyluridine 4-Hydroxy-5-methyl-2-mercaptopyrimidine 2,2'-Anhydro-5-methyluridine Dicumyl peroxide Thymidine
Uracil Cytosine
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Preparation Products

Zidovudine

Thymine Suppliers

Global( 647)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Blue Jet Healthcare Ltd +91-02222071691 +91-9082861262 Mumbai, India 86 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Central Drug House(P) Ltd. 91-11-49404040 New Delhi, India 6160 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
LOBA CHEMIE PVT.LTD. 91-22-6663 6699 Mumbai, India 3077 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Supplier Advantage
Blue Jet Healthcare Ltd 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Triveni chemicals 58
Central Drug House(P) Ltd. 58
SynZeal Research Pvt Ltd 58
LOBA CHEMIE PVT.LTD. 58
TCI Chemicals (India) Pvt. Ltd. 58
Otto Chemie Pvt. Ltd. 58

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Thymine Spectrum

Thymine(65-71-4)MSThymine(65-71-4)1HNMRThymine(65-71-4)13CNMRThymine(65-71-4)IR1Thymine(65-71-4)IR2Thymine(65-71-4)RamanThymine(65-71-4)ESR

65-71-4(Thymine)Related Search:

1,3-Dimethylurea 1,3-Dihydroxyacetone Butylated Hydroxytoluene 2,4-Dichloro-5-methylpyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid
3-Diethylaminophenol Chrysin Triclosan Solvent Red 43 Sulfamerazine
Pirimiphos-methyl 5-Methyluridine Stavudine ZIDOVUDINE RELATED COMPOUND B (25 MG) (3'-CHLORO-3'-DEOXYTHYMIDINE) 5,5'-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6'-dichloro-3-hydroxy-3,3'-biindoline-2,2'-dione
6-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid Thymidine Zidovudine
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4(1H,3H)-Pyrimidinedione,5-methyl-2 5-Methylpyrimidine-2,4-dione thymin(purinebase) THYMINE LABOTEST-BB LT00848102 THYMINE extrapure 1-Thia-4,8-diazaspiro[4.5]decan-3-one, 8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]- 1-Thia-4,8-diazaspiro[4.5]decan-3-one, 8-[3-(2-chlorophenothiazin-10-yl)propyl]- 8-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one Clospirazine Thymine,2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil 2,6-Dioxy-5-Methyl- pyriMidine 5-Methyl-1H-pyrimidine-2,4-dione 5-Methylpyridine-2,4-(1H,3H)-dione ThyMine, 99% 100GR ThyMine, 99% 25GR ThyMine, 99% 5GR Zidovudine EP IMpurity C 2,4(1H,3H)-Pyrimidinedione,5-methyl- 2,4-Dihydroxy-5-methylpyrimidin 3h)-pyrimidinedione,5-methyl-4(1h METHYL(5-) URACIL 5-METHYLPYRIMIDINE-2,4-DIOL 5-METHYL-2,4-DIHYDROXYPYRIMIDINE 5-METHYL-1,2,4-DIHYDROXYPYRIMIDINE 2,4-DIHYDROXY-5-METHYLPYRIMIDINE 5-METHYLURACIL 2,4(1H,3H)-Pyrimidinedione, 5-methyl- (9CI) D-THYMIDINE THYMINE PLANT CELL CULTURE TESTED THYMINE CELL CULTURE TESTED Thymine,>99% ThymineForBiochemistry99+% Thymine(5-MethylUracil) Thymine, 97+% Thymine Vetec(TM) reagent grade, 99% Stavudine Impurit Ⅰ:5-Methyl-2,4(1H,3H)-pyrimidinedione( Thymine) Zidovudine ImpuritⅢ:ThyMine Zidovudine and Lamivudine Tablets Impurit Ⅲ:ThyMine Thymine(Zidovudine Related Compound C) Zidovudine EP Impurity C(Thymine) Zidovudine Impurity 3(Zidovudine EP Impurity C) Thymine > hymine Stavudine EP impurity A Zidovudine EP Impurity C/ Zidovudine Related Compound C (Stavudine EP Impurity A/ Thymine) Stavudine EP Impurity A (Zidovudine EP Impurity C/ Zidovudine Related Compound C/ Thymine) Thymine 98% (HPLC) Zidovudine Impurity CQ: What is Zidovudine Impurity C Q: What is the CAS Number of Zidovudine Impurity C Q: What is the storage condition of Zidovudine Impurity C Q: What are the applications of Zidovudine Impurity C Methylpyrimidine-2,4(1H,3H)-dione Zidovudine Related Compound C (thymine) (1724532) 5-Methyl-2,4(1H,3H)-pyrimidinedione THYMIN 5-Methylpyrimidine-2,4(1H,3H)-dione Zidovudine Related CoMpound C 5-METHYLURACIL 2,4-DIHYDROXY-5-METHYLPYRIMIDINE 5-Methyl-2,4-dioxypyrimidine 2,4(1H,3H)-Pyrimidinedione, 5-methyl-