ChemicalBook > Product Catalog >API >Fluid, Electrolyte, and Acid-Base Balance >Electrolyte Balance Pharmacology >Etidronic Acid
Etidronic Acid
- CAS No.
- 2809-21-4
- Chemical Name:
- Etidronic Acid
- Synonyms
- HEDP;ETIDRONIC ACID;DEQUEST 2010;HEDP2NA;ehdp;1-diphosphonic acid;1-HYDROXYETHYLIDENE-1;1-HYDROXYETHANE-1,1-DIPHOSPHONIC ACID;HEDPA;hydroxy ethylidene diphosphoric acid
- CBNumber:
- CB4719658
- Molecular Formula:
- C2H8O7P2
- Molecular Weight:
- 206.03
- MOL File:
- 2809-21-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/12/18 14:08:52
| Melting point | 198~199℃ |
|---|---|
| Boiling point | 578.8±60.0 °C(Predicted) |
| Density | 1.45 (60% aq.) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 1.35, 2.87, 7.03, 11.3(at 25℃) |
| form | Powder |
| color | white |
| PH | pH (1.7→100, 25℃) : 1.3～1.8 |
| Water Solubility | Soluble in water. |
| Merck | 14,3863 |
| BRN | 1789291 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | DBVJJBKOTRCVKF-UHFFFAOYSA-N |
| LogP | -3.5 |
| CAS DataBase Reference | 2809-21-4(CAS DataBase Reference) |
| EPA Substance Registry System | Etidronic acid (2809-21-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 37/38-41-22 | |||||||||
| Safety Statements | 26-39 | |||||||||
| RIDADR | UN 3265 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | SZ8562100 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29319090 | |||||||||
| Hazardous Substances Data | 2809-21-4(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 oral in mouse: 1800mg/kg | |||||||||
| NFPA 704 |
|
Etidronic Acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | H6773 | Etidronic acid 60% aqueous solution | 2809-21-4 | 100G | ₹6473.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H6773 | Etidronic acid 60% aqueous solution | 2809-21-4 | 500G | ₹17439.08 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0587 | 1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L) | 2809-21-4 | 25G | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0587 | 1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L) | 2809-21-4 | 500G | ₹6800 | 2022-05-26 | Buy |
Etidronic Acid Chemical Properties,Uses,Production
Chemical Properties
light beige powder
Uses
Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM.
Definition
ChEBI: A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
in vitro
Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, and induces p53 mutation in MCF-7 cells.
Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
Etidronic Acid Preparation Products And Raw materials
Raw materials
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Global( 508)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| New Alliance Dye Chem Pvt Ltd | +91-9820112338 +91-9820112338 | Maharashtra, India | 104 | 58 | Inquiry |
| Bhakti Chemicals Pvt Ltd | +91-9820076785 +91-9819969093 | Mumbai, India | 18 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Neelam Aqua & Speciality Chem. (P) Ltd. | +91-9829069545 +91-9829060543 | Rajasthan, India | 38 | 58 | Inquiry |
| Adinath Auxi Chem Industry | 08048978185 | Gujarat, India | 1 | 58 | Inquiry |
| Ozone Enterprise | 08048612908 | Ahmedabad, India | 11 | 58 | Inquiry |
| Advance Chemical Sales Corporation | 08046056424 | Delhi, India | 39 | 58 | Inquiry |
| Exemplar | 08046045744 | Delhi, India | 17 | 58 | Inquiry |
| Saraf Resin & Chemicals Private Limited | 09700925769 | Hyderabad, India | 28 | 58 | Inquiry |
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ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID, 95+%
(1-Hydroxyethylidene)biphosphonic acid
Hydroxyethylidene Diphosphonic acid (HEDP)
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dequest2015
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1-hydroxy-1,1-diphosphonoethane
1-Hydroxyethanediphosphonica
1-hydroxyethanediphosphonicacid
1-Hydroxyethylene-1,1-diphosphoricacid
hydroxyethane-1,1-diphosphonicacid
hydroxyethanediphosphonicacid
Hydroxyethylidene-1,1-diphosphonicacid(HEDP)
oxyethylidenediphosphonicacid
Phosphonicacid,(1-hydroxyethylidene)bis-
phosphonicacid,1-hydroxy-1,1-ethanediylester
turpinalsl
1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID
1-HYDROXYETHANE-1,1-BIS(PHOSPHONIC ACID)
1-HYDROXYETHYLIDENEDIPHOSPHONIC ACID
(1-HYDROXY-1-PHOSPHONO-ETHYL)-PHOSPHONIC ACID
ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID
Etidronic Acid Monohydrate (1 g)
1-Hydroxyethylidene-1,1-Diphosphonic Acid/HEDP Powder
(1-Hydroxyethane-1,1-diyl)diphosphonic acid
1-Hydroxyethylidene-1,1-diphosphonic Acid
Etidronic Acid
Etidronate (Didronel)
Etidronic acid,60% in water
1-Hydroxyethane-1,1-diphosphonic acid, 60 wt.% solution in H2O
Etidronic acid Monohydrate (HEDP)
Etidronic acid 60% aqueous solution
HDEPA
OEDFK
HydroxyEthylidene-1,1-DiphosphonicAcid
Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-
1-Hydroxy Ethylidene-1, 1-Diphosphonic Acid (Hedp)60%
Etidronic acid 50% 60% 90%
HEDP 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid
Scale and Corrosion Inhibitor HEDP 60% 90%
60% 1-Hydroxyethane-1,1-bis(phosphonic acid) Solution