Risedronic acid
- CAS No.
- 105462-24-6
- Chemical Name:
- Risedronic acid
- Synonyms
- RISEDRONATE;RISEDRONIC ACID;RESEDRONIC ACID;Risedronic Acid RS;Risedronate sodium≥97%;3-(Acetic acid)Pyridine;Risedronic acid (Actonel);RISEDRONIC ACID MONOHYDRATE;Risedronate (Risedronic Acid);Risedronic acid (Risedronate)
- CBNumber:
- CB1118762
- Molecular Formula:
- C7H11NO7P2
- Molecular Weight:
- 283.11
- MOL File:
- 105462-24-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/11 18:14:38
| Melting point | >232°C (subl.) |
|---|---|
| Boiling point | 692.3±65.0 °C(Predicted) |
| Density | 1.870±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated) |
| pka | 1.41±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| CAS DataBase Reference | 105462-24-6(CAS DataBase Reference) |
| EPA Substance Registry System | Phosphonic acid, P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis- (105462-24-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
Risedronic acid Chemical Properties,Uses,Production
Uses
Risedronic Acid is a pyridinyl biphosphonate bone resorption inhibitor. It is a potentially useful biophosphonate for bone resorption analysis.
Definition
ChEBI: Risedronic acid is a member of pyridines. It is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease. It functions by preventing resorption of bone.
Mode of action
Risedronatic acid binds to bone hydroxyapatite. Bone resorption causes local acidification, releasing risedronic acid which is that taken into osteoclasts by fluid-phase endocytosis. Endocytic vesicles are acidified, releasing risedronic acid to the cytosol of osteoclasts where they induce apoptosis through inhbition of farnesyl pyrophosphate synthase. Inhibition of osteoclasts results in decreased bone resorption.
Risedronic acid Preparation Products And Raw materials
Raw materials
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105462-24-6(Risedronic acid)Related Search:
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1-Hydroxy-2-(3-pyridyl)-ethan-1,1-bis-phosphonic acid
RISEDRONIC ACID: RISEDRONIC ACID MONOHYDRATE
1-Hydroxy-2-(3-pyridinyl)ethylidenebisphosphonicacidmonohydrate
1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE]BISPHOSPHONIC ACID
3-(Acetic acid)Pyridine
Phosphonic acid,P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-
P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-phosphonic acid
Risedronic acid (Actonel)
(1-Hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid monohydrate
RISEDRONIC ACID
RISEDRONIC ACID MONOHYDRATE
RISEDRONATE
RESEDRONIC ACID
Risedronate sodium≥97%
(1-HYDROXY-1-PHOSPHONO-2-PYRIDIN-3-YL-ETHYL)PHOSPHONIC ACID
Risedronic acid(Sodium risedronate intermediate)
Risedronic Acid RS
Phosphonic acid, [1-hydroxy-2-(3-pyridinyl)ethylidene]bis-
(1-Hydroxy-2-(pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid
Risedronate (Risedronic Acid)
Risedronic acid (Risedronate)
TIANFUCHEM--105462-24-6--High purity Risedronic acid factory price
5-(1H-Pyrrol-1-y1)-2-
mercaptobenzimidazole
105462-24-6
C7H11NO7P2
C7H7NO7P2D4
API
(intermediate of risedronate sodium
Risedronate