2-Ethoxyethanol
- CAS No.
- 110-80-5
- Chemical Name:
- 2-Ethoxyethanol
- Synonyms
- Ethoxyethanol;ETHYL GLYCOL;ETHYLENE GLYCOL MONOETHYL ETHER;CELLOSOLVE;ETHYL CELLOSOLVE;EGEE;Ethanol, 2-ethoxy-;Glycol monoethyl ether;ETHYLENE GLYCOL ETHYL ETHER;ethoxyethano
- CBNumber:
- CB6852821
- Molecular Formula:
- C4H10O2
- Molecular Weight:
- 90.12
- MOL File:
- 110-80-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/7 16:47:56
| Melting point | -100 °C |
|---|---|
| Boiling point | 135 °C(lit.) |
| Density | 0.93 g/mL at 25 °C(lit.) |
| vapor density | 3.1 (vs air) |
| vapor pressure | 3.8 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | 107.6 °F |
| storage temp. | Store below +30°C. |
| solubility | water: miscible |
| form | Liquid |
| pka | 14.44±0.10(Predicted) |
| color | Clear, colorless |
| Odor | Sweetish; mild, pleasant, ethereal. |
| Odor Threshold | 0.58ppm |
| explosive limit | 1.8-15.7%(V) |
| Water Solubility | miscible |
| FreezingPoint | -70℃ |
| λmax |
λ: 215 nm Amax: 1.00 λ: 225 nm Amax: 0.50 λ: 250 nm Amax: 0.20 λ: 305 nm Amax: 0.01 |
| Merck | 14,3750 |
| BRN | 1098271 |
| Exposure limits | TLV-TWA skin 5 ppm (18.5 mg/m3) (ACGIH). . |
| Dielectric constant | 29.6（24℃） |
| Stability | Stable. Readily forms explosive mixtures with air - note the wide explosion range. Vapour may travel considerable distance to a source of ignition. Flammable. Incompatible with strong acids, strong bases, strong oxidizing agents, aluminium, alkalies. |
| LogP | 0.32 at 20℃ |
| CAS DataBase Reference | 110-80-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 2-ethoxy-(110-80-5) |
| EPA Substance Registry System | 2-Ethoxyethanol (110-80-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H331-H360FD | |||||||||
| Precautionary statements | P201-P210-P301+P312+P330-P304+P340+P311-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 60-61-10-20/21/22-20/22 | |||||||||
| Safety Statements | 53-45 | |||||||||
| RIDADR | UN 1171 3/PG 3 | |||||||||
| OEB | B | |||||||||
| OEL | TWA: 0.5 ppm (1.8 mg/m3) [skin] | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | KK8050000 | |||||||||
| Autoignition Temperature | 460 °F | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29094990 | |||||||||
| Toxicity | Acute oral LD50 for guinea pigs 1,400 mg/kg, mice 2,451 mg/kg, rats 3,000 mg/kg, rabbits 3,100 mg/kg (quoted, RTECS, 1985). | |||||||||
| IDLA | 500 ppm | |||||||||
| NFPA 704 |
|
2-Ethoxyethanol price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.00857 | 2-Ethoxyethanol (stabilised) for synthesis | 110-80-5 | 1IN28008572500 | ₹96.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.00857 | 2-Ethoxyethanol (stabilised) for synthesis | 110-80-5 | 1L | ₹6010 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.00857 | 2-Ethoxyethanol (stabilised) for synthesis | 110-80-5 | 2.5L | ₹7780 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1550 | 2-Ethoxyethanol Pharmaceutical Secondary Standard; Certified Reference Material | 110-80-5 | 3X1.2ML | ₹9103.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.00857 | 2-Ethoxyethanol (stabilised) for synthesis | 110-80-5 | 25L | ₹49090 | 2022-06-14 | Buy |
2-Ethoxyethanol Chemical Properties,Uses,Production
Description
2-Ethoxyethanol is a stable, colorless, flammable liquid, synthetically produced throughout the world. It belongs to a larger group of glycol ether solvents. 2-Ethoxyethanol is commercially referred to as Ethyl Cellosolve or Cellosolve, a trademark registered by Union Carbide in 1924. It was first synthesized to have the same chemical properties of both alcohols and ethers (hydrophilic and lipophilic) but less volatile, which improves production characteristics. The glycol ethers are made by reacting anhydrous alcohols with ethylene oxide.
Chemical Properties
2-Ethoxyethanol is a colorless, viscous liquid with a sweetish odor
Physical properties
Clear, colorless liquid with a sweetish odor. Experimentally determined detection and recognition odor threshold concentrations were 1.1 mg/m3 (300 ppbv) and 2.0 mg/m3 (540 ppbv), respectively (Hellman and Small, 1974).
Uses
2-Ethoxyethanol is widely used as an industrial solvent and production intermediate. It is produced by the reaction of ethylene oxide with ethanol. The glycol ethers are miscible in polar and nonpolar solutions, which make them useful solvents in paints and surface coatings, stains, lacquers, inks, and dyes. Additional uses include industrial deicing, hydraulic fluids, and cleaning agents. 2-Ethoxyethanol was once used in cosmetic products but is no longer used due to toxicity associated with dermal absorption. Global production has been on the decline in recent years based on demonstrated toxicity through oral, dermal, and inhalation routes of exposure. The use of ethylene glycol ethers has largely been replaced by relatively safer substitutes, primarily propylene glycol ethers; however, their use as a solvent and chemical process intermediate poses potential for release into the environment.
Definition
ChEBI: A hydroxyether that is the ethyl ether derivative of ethylene glycol.
General Description
A clear colorless liquid. Flash point of 120°F. Less dense than water. Its vapors are heavier than air.
Air & Water Reactions
Flammable. Water soluble.
Reactivity Profile
ETHYLENE GLYCOL MONOMETHYL ETHER may react with oxidizing materials, i.e. hydrogen peroxide, to form peroxides. 2-Ethoxyethanol dissolves many oils, resins and waxes.
Hazard
Toxic by skin absorption. Moderate fire risk.
Health Hazard
Some eye irritation. Inhalation of vapors causes irritation of nose.
Fire Hazard
Special Hazards of Combustion Products: Toxic gases, such as carbon monoxide, may be produced in fire.
Chemical Reactivity
Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Safety Profile
Moderately toxic by ingestion, skin contact, intravenous, and intraperitoneal routes. Mildly toxic by inhalation and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. A mild eye and skin irritant. Combustible when exposed to heat or flame; can react with oxidzing materials. Moderate explosion hazard in the form of vapor when exposed to heat or flame. Mxture with hydrogen peroxide + polyacrylamide gel + toluene is explosive when dry. To fight fire, use alcohol foam, dry chemical. See also GLYCOL ETHERS.
Potential Exposure
This material is used as a solvent for nitrocellulose and alkyd resins in lacquers; as a solvent for printing inks; in dyeing leathers and textiles; in the formulation of cleaners and varnish removers; as an anti-icing additive in brake fluids and auto and aviation fuels.
Environmental Fate
Biological. Bridié et al. (1979) reported BOD and COD values of 1.03 and 1.92 g/g using
filtered effluent from a biological sanitary waste treatment plant. These values were determined
using a standard dilution method at 20 °C for a period of 5 d. When a sewage seed was used in a
separate screening test, a BOD value of 1.27 g/g was obtained. Similarly, Heukelekian and Rand
(1955) reported a 5-d BOD value of 1.42 g/g which is 72.4% of the ThOD value of 1.96 g/g.
Photolytic. Grosjean (1997) reported a rate constant of 1.87 x 10-11 cm3/molecule?sec at 298 K
for the reaction of 2-ethoxyethanol and OH radicals in the atmosphere. Based on an atmospheric
OH radical concentration of 1.0 x 106 molecule/cm3, the reported half-life of methanol is 0.35 d
(Grosjean, 1997). Stemmler et al. (1996) reported a rate constant of 1.66 x 10-11 cm3/molecule?sec
for the OH radical-initiated oxidation of 2-ethoxyethanol in synthetic air at 297 K and 750 mmHg.
Major reaction products identified by GC/MS (with their yields) were ethyl formate, 34%;
ethylene glycol monoformate, 36%; ethylene glycol monoacetate, 7.8%; and ethoxyacetaldehyde,
24%.
Chemical/Physical. 2-Ethoxyethanol will not hydrolyze (Kollig, 1993).
At an influent concentration of 1,024 mg/L, treatment with GAC resulted in an effluent
concentration of 886 mg/L. The adsorbability of the carbon used was 28 mg/g carbon (Guisti et
al., 1974).
Shipping
UN1171 Ethylene glycol monoethyl ether, Hazard Class: 3; Labels: 3-Flammable liquid.
Purification Methods
Dry it with CaSO4 or K2CO3, filter and fractionally distil it. Peroxides can be removed by refluxing with anhydrous SnCl2 or by filtration under slight pressure through a column of activated alumina. [Beilstein 1 IV 2377.]
Incompatibilities
May form explosive mixture with air. Strong oxidizers may cause fire and explosions. Attacks some plastics, rubber and coatings. Able to form peroxides. Incompatible with strong acids; aluminum and its alloys
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≧100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal
2-Ethoxyethanol Preparation Products And Raw materials
Raw materials
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SHIVAM INDUSTRIES | +91-9820823043 +91-9820823043 | Mumbai, India | 30 | 58 | Inquiry |
| Nyne Organics Pvt Ltd | +91-9920180386 +91-9920180386 | Mumbai, India | 53 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Newage Industrial Oils Pvt Ltd NIOPL | +91-846005276 +91-8866035309 | Gujarat, India | 11 | 58 | Inquiry |
| Advance Petrochemicals Ltd | +91-9081998855 +91-7573006525 | Gujarat, India | 11 | 58 | Inquiry |
| Swastik Oil | +91-9426313461 +91-9426313461 | Gujarat, India | 13 | 58 | Inquiry |
| Advance Petrochemicals Limited | 08046030618 | Ahmedabad, India | 9 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Dr Prem's Molecules Pvt. Ltd. | +91 9825310038 | New Delhi, India | 547 | 50 | Inquiry |
| Supplier | Advantage |
|---|---|
| SHIVAM INDUSTRIES | 58 |
| Nyne Organics Pvt Ltd | 58 |
| JSK Chemicals | 58 |
| Newage Industrial Oils Pvt Ltd NIOPL | 58 |
| Advance Petrochemicals Ltd | 58 |
| Swastik Oil | 58 |
| Advance Petrochemicals Limited | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| ALPHA CHEMIKA | 43 |
| Dr Prem's Molecules Pvt. Ltd. | 50 |
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