Uracil
- CAS No.
- 66-22-8
- Chemical Name:
- Uracil
- Synonyms
- PYRIMIDINE-2,4(1H,3H)-DIONE;PYRIMIDINE-2,4-DIOL;Ura;2,4-DIHYDROXYPYRIMIDINE;2,4(1H,3H)-PYRIMIDINEDIONE;Uracyl;Uracll;Cellocidin;2,6-Dihydroxypyrimidine;1H-Pyrimidine-2,4-dione
- CBNumber:
- CB8376824
- Molecular Formula:
- C4H4N2O2
- Molecular Weight:
- 112.09
- MOL File:
- 66-22-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/2 15:22:07
| Melting point | >300 °C (lit.) |
|---|---|
| Boiling point | 209.98°C (rough estimate) |
| Density | 1.4421 (rough estimate) |
| refractive index | 1.4610 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 9.45(at 25℃) |
| color | White to slightly yellow |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,9850 |
| BRN | 606623 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | ISAKRJDGNUQOIC-UHFFFAOYSA-N |
| LogP | -1.037 (est) |
| CAS DataBase Reference | 66-22-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Uracil(66-22-8) |
| EPA Substance Registry System | Uracil (66-22-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YQ8650000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
Uracil price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | U0750 | Uracil ≥99.0% | 66-22-8 | 5G | ₹2486.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U0750 | Uracil ≥99.0% | 66-22-8 | 25G | ₹2808.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U1128 | Uracil BioReagent, suitable for cell culture | 66-22-8 | 25G | ₹4073.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U0750 | Uracil ≥99.0% | 66-22-8 | 100G | ₹8402.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U1128 | Uracil BioReagent, suitable for cell culture | 66-22-8 | 100G | ₹9845.7 | 2022-06-14 | Buy |
Uracil Chemical Properties,Uses,Production
Description
Uracil is a pyrimidine base and a fundamental component of RNA where it binds to adenine via hydrogen bonds. It is converted into the nucleoside uridine through the addition of a ribose moiety, then to the nucleotide uridine monophosphate by the addition of a phosphate group.
Chemical Properties
Crystalline needles. Soluble in hot water, ammonium hydroxide, and other alkalies; insoluble in alcohol and ether.
Uses
Uracil (Lamivudine EP Impurity F) is a nitrogenous base on RNA nucleosides.
Definition
uracil: A pyrimidine derivative andone of the major component bases ofnucleotides and the nucleic acidRNA.
General Description
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Uracil is one of the nucleotide bases of RNA. It is the precursor of DNA′s thymine. It acts like a carrier of genetic data and is hooked up with a ribose and three phosphates to form a ribonucleoside triphosphate once a human body produces nucleotides.
Safety Profile
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Uracil crystallises from water (m 339-341o) and m 338o after sublimation in high vacuum. Its solubility in H2O at 20o is 1g/300mL. [Beilstein 24 H 312, 24 I 312, 24 II 169, 24 III/IV 1193.]
Uracil Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
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| ANJI BIOSCIENCES | +91-9000100077 +91-9000100077 | Hyderabad, India | 430 | 58 | Inquiry |
| ULTIMA CHEMICALS | +91 7208029458 | Mumbai, India | 95 | 58 | Inquiry |
| BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT., | +91-91-8421973722 +91-9869455944 | Telangana, India | 31 | 58 | Inquiry |
| JIVICHEM SYNTHESIS PVT LTD | +91-7028392790 +91-7028392790 | Maharashtra, India | 337 | 58 | Inquiry |
| R SCIENTIFIC | +919000280374 | Hyderabad, India | 143 | 58 | Inquiry |
| AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
| GGC Chemicals And Pharmaceuticals Pvt Ltd | +919824336772 | Gujarat, India | 14 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| DeFINE CHEMICALS | +91-8010769889 +91-9320057099 | Maharashtra, India | 120 | 58 | Inquiry |
| Alfa Omega Pharma | +91-8050045945 +91-9972665399 | Maharashtra, India | 126 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ANJI BIOSCIENCES | 58 |
| ULTIMA CHEMICALS | 58 |
| BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT., | 58 |
| JIVICHEM SYNTHESIS PVT LTD | 58 |
| R SCIENTIFIC | 58 |
| AMINO ORGANICS | 58 |
| GGC Chemicals And Pharmaceuticals Pvt Ltd | 58 |
| JSK Chemicals | 58 |
| DeFINE CHEMICALS | 58 |
| Alfa Omega Pharma | 58 |
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