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N,N'-DICYCLOHEXYLUREA

N,N'-DICYCLOHEXYLUREA Structure
CAS No.
2387-23-7
Chemical Name:
N,N'-DICYCLOHEXYLUREA
Synonyms
1,3-DICYCLOHEXYLUREA;Indapamide Impurity 1;Dicyclohexylcarbodiamide;NSC 30023;NSC 17013;AURORA KA-3582;Lomustine USP RC C;N,N'-DICYCLOHEXYLUREA;n,n’-dicyclohexyl-ure;N,N'-DICYCLOHEXYLUREA
CBNumber:
CB2314754
Molecular Formula:
C13H24N2O
Molecular Weight:
224.34
MOL File:
2387-23-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:12

N,N'-DICYCLOHEXYLUREA Properties

Melting point 232-233 °C(lit.)
Boiling point 408℃
Density 1.02
refractive index 1.4832 (estimate)
Flash point 158℃
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Liquid
pka 13.89±0.20(Predicted)
color Clear
Stability Hygroscopic
InChIKey ADFXKUOMJKEIND-UHFFFAOYSA-N
CAS DataBase Reference 2387-23-7(CAS DataBase Reference)
EPA Substance Registry System N,N'-Dicyclohexylurea (2387-23-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  22-51/53
Safety Statements  61
WGK Germany  3
TSCA  Yes
HS Code  29242100
NFPA 704
1
0 0

N,N'-DICYCLOHEXYLUREA price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2924 Lomustine Related Compound C certified reference material, pharmaceutical secondary standard 2387-23-7 500MG ₹51527 2022-06-14 Buy
Sigma-Aldrich D80800 N,N′-Dicyclohexylurea 98% 2387-23-7 25G ₹5560 2022-06-14 Buy
Sigma-Aldrich(India) D80800 N,N′-Dicyclohexylurea 98% 2387-23-7 25G ₹5560 2022-06-14 Buy
TCI Chemicals (India) D0441 1,3-Dicyclohexylurea min. 98.0 % 2387-23-7 25G ₹2900 2022-05-26 Buy
TCI Chemicals (India) D0441 1,3-Dicyclohexylurea min. 98.0 % 2387-23-7 500G ₹16400 2022-05-26 Buy
Product number Packaging Price Buy
PHR2924 500MG ₹51527 Buy
D80800 25G ₹5560 Buy
D80800 25G ₹5560 Buy
D0441 25G ₹2900 Buy
D0441 500G ₹16400 Buy

N,N'-DICYCLOHEXYLUREA Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.

Preparation

An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine).

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AURORA KA-3582 n,n’-dicyclohexyl-ure N,N'-DICYCLOHEXYLUREA N,N,-Dicyclohexylurea98.% N,N'-Carbonylbis(cyclohexanamine) NSC 17013 NSC 30023 LoMustine Related CoMpound C 1,3-Dicyclohexylurea for synthesis Lomustine EP Impurity B 5-cyanobenzene-1,3-dicarboxylic acid 1,3-Dicyclohexylurea > Lomustine USP RC C Urea, N,N'-dicyclohexyl- Lomustine Related Compound C (1,3-Dicyclohexylurea) (1369442) 1,3-DICYCLOHEXYLUREA Dicyclohexylcarbodiamide Indapamide Impurity 1 Lomustine USP Related Compound C Lomustine EP Impurity C Lomustine Impurity 3(Lomustine EP Impurity C)(Lomustine USP RC C) 1,3-dicyclohexylurea - impurity 1,3-Dicyclohexylurea, ≥ 98.0% n,n''-dicyclohexylurea N,N'-DICYCLOHEXYLUREA 2387-23-7 C13H24N2O C6H11NHCONHC6H11 Organic Building Blocks Ureas Building Blocks Carbonyl Compounds Finasteride Carbonyl Compounds Organic Building Blocks Ureas