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(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Structure
CAS No.
1417997-93-3
Chemical Name:
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
Synonyms
22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
CBNumber:
CB23373154
Molecular Formula:
C22H19NO3
Molecular Weight:
345.39
MOL File:
1417997-93-3.mol
Modify Date:
2024/7/2 8:55:03
Request For Quotation

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Properties

Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: soluble
form A solid
pka 8.76±0.23(Predicted)
color White to off-white

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Chemical Properties,Uses,Production

Description

HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).

Uses

(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Preparation Products And Raw materials

Raw materials

2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl)-, ethyl ester, (E)- 7-Methoxycoumarin

Preparation Products

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Suppliers

Global( 65)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13183 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20294 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 5225 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
Career Henan Chemica Co 58
Zhejiang J&C Biological Technology Co.,Limited 58
Henan Alfa Chemical Co., Ltd 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Henan Fengda Chemical Co., Ltd 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
RD International Technology Co., Limited 58

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Spectrum

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide(1417997-93-3)1HNMR

1417997-93-3((E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide)Related Search:

3-Piperidinecarboxamide, N-methyl-N-(phenylmethyl)-1-[[4-(trifluoromethyl)phenyl]methyl]-, hydrochloride (1:1) N-benzyl-N-Methyl-1-(4-(trifluoroMethyl)benzyl)piperidine-3-carboxaMide
INVIVO-7933 (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide (2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide 2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)- HDAC8-IN-22d HDAC8 inhibitor 22d CS-2693 HDAC8 inhibitor 1 MDK-7933 HDAC8-IN-1 ,MDK7933 (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 22d HDAC8-IN-1 HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1 HDAC8-IN-1(22d) (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide 1417997-93-3 417997-93-3