(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
![(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Structure](CAS/20180527/GIF/1417997-93-3.gif)
- CAS No.
- 1417997-93-3
- Chemical Name:
- (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- Synonyms
- 22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
- CBNumber:
- CB23373154
- Molecular Formula:
- C22H19NO3
- Molecular Weight:
- 345.39
- MOL File:
- 1417997-93-3.mol
- Modify Date:
- 2024/7/2 8:55:03
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Chemical Properties,Uses,Production
Description
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).
Uses
(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 65)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
Henan Alfa Chemical Co., Ltd | +8618339805032 | China | 13183 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20294 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | China | 5225 | 58 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9268 | 58 | Inquiry |
1417997-93-3((E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide)Related Search:
INVIVO-7933
(E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
(2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)-
HDAC8-IN-22d
HDAC8 inhibitor 22d
CS-2693
HDAC8 inhibitor 1
MDK-7933
HDAC8-IN-1 ,MDK7933
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
22d
HDAC8-IN-1
HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
HDAC8-IN-1(22d)
(E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
1417997-93-3
417997-93-3