Pitavastatin Impurity 2

Pitavastatin Impurity 2 Structure
CAS No.
1187966-93-3
Chemical Name:
Pitavastatin Impurity 2
Synonyms
Pitavastatin Impurity 114;Pitavastatin calcium impurity;Pitavastatin Benzophenanthridine; (3R,5S)-5-(6-cyclopropyl-10-fluorobenzo;Pitavastatin Benzophenanthridine Impurity;Benzo[k]phenanthridine-8-pentanoic acid, 6-cyclopropyl-10-fluoro-β,δ-dihydroxy-, (βR,δS)-;(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid;3-(3-((1S,3R)-4-carboxy-1,3-dihydroxybutyl)oxiran-2-yl)-2- cyclopropyl-4-(4-fluorophenyl)quinoline 1-oxide;(3R,5S)-5-(6-cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic acid? (Pitavastatin Impurity)
CBNumber:
CB23386062
Molecular Formula:
C25H22FNO4
Molecular Weight:
419.45
MOL File:
1187966-93-3.mol
Modify Date:
2023/4/23 13:52:06

Pitavastatin Impurity 2 Properties

Boiling point 752.0±60.0 °C(Predicted)
Density 1.444±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Methanol (Slightly)
form Solid
pka 4.23±0.10(Predicted)
color Pale Beige to Light Beige
Stability Hygroscopic

Pitavastatin Impurity 2 Chemical Properties,Uses,Production

Uses

(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is an impurity of pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic.

Pitavastatin Impurity 2 Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Pitavastatin Benzophenanthridine Impurity Pitavastatin calcium impurity (3R,5S)-5-(6-cyclopropyl-10-fluorobenzo Benzo[k]phenanthridine-8-pentanoic acid, 6-cyclopropyl-10-fluoro-β,δ-dihydroxy-, (βR,δS)- Pitavastatin Benzophenanthridine 3-(3-((1S,3R)-4-carboxy-1,3-dihydroxybutyl)oxiran-2-yl)-2- cyclopropyl-4-(4-fluorophenyl)quinoline 1-oxide (3R,5S)-5-(6-cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic acid? (Pitavastatin Impurity) Pitavastatin Impurity 114 1187966-93-3