PITAVASTATIN LACTONE

PITAVASTATIN LACTONE Structure
CAS No.
141750-63-2
Chemical Name:
PITAVASTATIN LACTONE
Synonyms
PITAVASTATIN LACTONE;Pitavastatin Impurity A;Pitavastatin Impurity 4;Pitavastatin Lactone D5;Pivastatin lactone impurity;Pitavastatin calcium lactone;Pitavastatin calcium impurity D; (4R,6S)-6-((E)-2-(2-cyclopropyl;Pitavastatin Lactone DISCONTINUED;PITAVASTATIN LACTONE ISO 9001:2015 REACH
CBNumber:
CB9649789
Molecular Formula:
C25H22FNO3
Molecular Weight:
403.45
MOL File:
141750-63-2.mol
Modify Date:
2023/7/12 13:55:41

PITAVASTATIN LACTONE Properties

Melting point 92-95°C
alpha D32 +8.84° (c = 0.92 in chloroform)
Boiling point 616.9±55.0 °C(Predicted)
Density 1.372±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform
form Powder
pka 13.25±0.40(Predicted)
color White to Off-White
Stability Hygroscopic

PITAVASTATIN LACTONE Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Powder

Uses

Lactone form of Pitavastatin; a HMG-CoA reductase inhibitor. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms.

PITAVASTATIN LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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PITAVASTATIN LACTONE Pitavastatin calciuM interMediates to 5, (4R, 6S, E) -6 - [2 - cyclopropyl-4 - (4 - fluorophenyl) -3 - quinoline - yl - vinyl] -4 - hydroxy -3,4,5,6 - tetrahydro-2H-pyran-2 - one Pitavastatin Lactone DISCONTINUED (4R,6S,E)-6-[2-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl]tetrahydro-4-hydroxypyran-2-one Pivastatin lactone impurity Pitavastatin Lactone/Itavastatin Lactone/(4R,6S,E)-6-[2-[2-Cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl] vinyl] tetrahydro-4-hydroxypyran-2-one (4R,6S)-6-((E)-2-(2-cyclopropyl Pitavastatin calcium impurity D (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one Pitavastatin Impurity A (4R,6S,E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl-ethenylvinyl]-4-hydroxyl-3,4,5,6-H-2H-pyran-2-etone Pitavastatin Impurity 4 Pitavastatin calcium lactone 2H-Pyran-2-one, 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-, (4R,6S)- PITAVASTATIN LACTONE ISO 9001:2015 REACH Pitavastatin Lactone D4Q: What is Pitavastatin Lactone D4 Q: What is the CAS Number of Pitavastatin Lactone D4 Q: What is the storage condition of Pitavastatin Lactone D4 Q: What are the applications of Pitavastatin Lactone D4 Pitavastatin Lactone D5 Pitavastatin LactoneQ: What is Pitavastatin Lactone Q: What is the CAS Number of Pitavastatin Lactone Q: What is the storage condition of Pitavastatin Lactone Q: What are the applications of Pitavastatin Lactone 141750-63-2 C25H22FNO3 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals All Inhibitors