25-DESACETYL RIFAMPICIN
- CAS No.
- 16783-99-6
- Chemical Name:
- 25-DESACETYL RIFAMPICIN
- Synonyms
- Aids070669;Aids-070669;DeacetylrifaMpin;Desacetylrifampin;DeacetylrifaMpicin;Desacetylrifampicin;25-DesacetylrifaMpin;25-deacetylrifampicin;25-DESACEYL RIFAMYCIN;25-O-DesacetylrifaMpin
- CBNumber:
- CB2365781
- Molecular Formula:
- C41H56N4O11
- Molecular Weight:
- 780.9
- MOL File:
- 16783-99-6.mol
- Modify Date:
- 2023/9/7 11:20:37
| Melting point | >300°C |
|---|---|
| Boiling point | 943.1±65.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.96±0.70(Predicted) |
| color | Dark Red to Black |
| Stability | Light Sensitive |
| InChIKey | KUJZTIJOBQNKDR-ACYBWPGYNA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H319-H360-H335 | |||||||||
| Precautionary statements | P201-P202-P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P304+P340-P305+P351+P338-P308+P313-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
25-DESACETYL RIFAMPICIN Chemical Properties,Uses,Production
Description
25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3].
Chemical Properties
Dark Red Solid
Uses
A metabolite of Rifampicin.
References
[1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315.
25-DESACETYL RIFAMPICIN Preparation Products And Raw materials
Raw materials
Preparation Products
25-DESACETYL RIFAMPICIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
| Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-13602409664 | China | 3635 | 55 | Inquiry |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016 | China | 9887 | 58 | Inquiry |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | China | 9911 | 50 | Inquiry |
| BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
16783-99-6(25-DESACETYL RIFAMPICIN)Related Search:
1of2
chevron_right