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PHENAMIL

PHENAMIL Structure
CAS No.
2038-35-9
Chemical Name:
PHENAMIL
Synonyms
PHENAMIL;phenylamil;phenamil methanesulfonate salt;Phenamil methanesulfonate (free base);3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide;3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-;3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide
CBNumber:
CB2384179
Molecular Formula:
C12H12ClN7O
Molecular Weight:
305.72
MOL File:
2038-35-9.mol
Modify Date:
2023/7/12 17:02:16
Request For Quotation

PHENAMIL Properties

Melting point >181°C (dec.)
Density 1.65±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >15 mg/mL
form solid
pka 8.10±0.46(Predicted)
color yellow

SAFETY

Risk and Safety Statements

WGK Germany  3

PHENAMIL Chemical Properties,Uses,Production

Enzyme inhibitor

This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility.

PHENAMIL Preparation Products And Raw materials

Raw materials

Preparation Products

PHENAMIL Suppliers

Global( 29)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
MP Biomedicals, Inc. 949 833 2500 United States 6566 81 Inquiry
Kainic.com 1- (858) 452-9925 United States 330 38 Inquiry
ASDI Incorporated 888 577 ASDI United States 6928 67 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
Fluorochem Ltd (01457) 868921 (4 lines) United Kingdom 6383 65 Inquiry
MOLEKULA Ltd. +44 (0) 1747 831066 United Kingdom 6152 66 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 94658 76 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; China 56354 58 Inquiry
Supplier Advantage
MP Biomedicals, Inc. 81
Kainic.com 38
ASDI Incorporated 67
3B Scientific Corporation 47
Fluorochem Ltd 65
MOLEKULA Ltd. 66
SIGMA-RBI 91
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

2038-35-9(PHENAMIL)Related Search:

phenamil receptor PHENAMIL METHANESULFONATE 5-AMINOPYRAZINE-2-CARBOXAMIDE PHENAMIL 6-CHLORO-2-PYRAZINECARBOXAMIDE
2-pyrazinoylguanidine 2-amino-3-chloro-5-methyl-pyrazine 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE 2,6-Pyrazinediamine(9CI) 3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE
PHENAMIL METHANESULFONATE 5-(N,N-HEXAMETHYLENE)-AMILORIDE 2-Amino-5-chloropyrazine (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE 3-AMINO-N-METHYLPYRAZINE-2-CARBOXAMIDE
2-Chloro-6-methylpyrazine
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PHENAMIL 3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE 3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt phenamil methanesulfonate salt phenylamil 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide 3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide 3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide 3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide Phenamil methanesulfonate (free base) 2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]- 2038-35-9 C12H12ClN7OCH3SO3H C12H12ClN7O Irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride. Cell Biology Cell Signaling and Neuroscience BioChemical Amiloride and Derivatives Monovalent Ion Channels Ion Channels Sodium Channel Modulators Voltage-gated Ion Channels