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ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Hydroxylamine >1-NAPHTHOHYDROXAMIC ACID

1-NAPHTHOHYDROXAMIC ACID

1-NAPHTHOHYDROXAMIC ACID Structure
CAS No.
6953-61-3
Chemical Name:
1-NAPHTHOHYDROXAMIC ACID
Synonyms
NSC 57457;Naphthohydroxamicacid;a-Naphthohydroxamic acid;1-NAPHTHOHYDROXAMIC ACID;1-NaphthohydroxamicAcid>alpha-naphthohydroxamicacid;1-NAPHTHOHYDROXAMIC ACID 98+%;HDAC Inhibitor XIX, Compound 2;n-hydroxy-1-naphthalenecarboxamid;1-Naphthalenecarbohydroximic acid
CBNumber:
CB2462406
Molecular Formula:
C11H9NO2
Molecular Weight:
187.19
MOL File:
6953-61-3.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:22
Request For Quotation

1-NAPHTHOHYDROXAMIC ACID Properties

Melting point 176-178 °C
Density 1.291±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥5mg/mL
form White solid
pka 8.91±0.30(Predicted)
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H312-H302-H332
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
Risk Statements  52
WGK Germany  3
RTECS  QJ1894500
HS Code  2928009090

1-NAPHTHOHYDROXAMIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 382177 HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 - Calbiochem The HDAC Inhibitor XIX, Compound 2, also referenced under CAS 6953-61-3, controls the biological activity of HDAC. This small molecule/inhibitor is pr 6953-61-3 50MG ₹14260 2022-06-14 Buy
TCI Chemicals (India) N0023 1-Naphthohydroxamic Acid 6953-61-3 1G ₹19700 2022-05-26 Buy
Product number Packaging Price Buy
382177 50MG ₹14260 Buy
N0023 1G ₹19700 Buy

1-NAPHTHOHYDROXAMIC ACID Chemical Properties,Uses,Production

Uses

1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6.

Biochem/physiol Actions

1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity.

1-NAPHTHOHYDROXAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

1-NAPHTHOHYDROXAMIC ACID Suppliers

Global( 72)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6846 75 Inquiry
Supplier Advantage
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
GIHI CHEMICALS CO.,LIMITED 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
ABCR GmbH & CO. KG 75

1-NAPHTHOHYDROXAMIC ACID Spectrum

1-NAPHTHOHYDROXAMIC ACID(6953-61-3)MS1-NAPHTHOHYDROXAMIC ACID(6953-61-3)1HNMR1-NAPHTHOHYDROXAMIC ACID(6953-61-3)13CNMR1-NAPHTHOHYDROXAMIC ACID(6953-61-3)IR1

6953-61-3(1-NAPHTHOHYDROXAMIC ACID)Related Search:

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Naphthalene-1-carbohydroximic acid N-Hydroxy-1-naphthalenecarboxamide a-Naphthohydroxamic acid NSC 57457 HDAC Inhibitor XIX, Compound 2 N-HYDROXYNAPHTHALENE-1-CARBOXAMIDE alpha-naphthohydroxamicacid n-hydroxy-1-naphthalenecarboxamid 1-NAPHTHOHYDROXAMIC ACID Naphthohydroxamicacid 1-NAPHTHOHYDROXAMIC ACID 98+% 1-Naphthalenecarbohydroximic acid HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 - Calbiochem 1-NaphthohydroxamicAcid> tubulin,anti-proliferation,deacetylate,HDAC8,Inhibitor,1 Naphthohydroxamic acid,hyperacetylated,1Naphthohydroxamic acid,acetylation,inhibit,clone,HDAC,Histone deacetylases,1-Naphthohydroxamic acid 1-Naphthalenecarboxamide, N-hydroxy- 6953-61-3 Hydroxylamines Hydroxylamines (N-Substituted) Hydroxylamines Hydroxylamines (N-Substituted)