TETRANDRINI DIMETHIODIDUM
- CAS No.
- 7601-55-0
- Chemical Name:
- TETRANDRINI DIMETHIODIDUM
- Synonyms
- Metubine;metubineiodide;methyl-curarin;metocurineiodide;TETRANDRINI DIMETHIODIDUM;dimethyltubocurarineiodide;Dimethylchondrocurarineiodide;d-tubocurarineiodidedimethylether;dimethyletherofd-tubocurarineiodide;(+)-o,o’-dimethylchondrocurarinediiodide
- CBNumber:
- CB2676607
- Molecular Formula:
- C40H48I2N2O6
- Molecular Weight:
- 906.63
- MOL File:
- 7601-55-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/17 21:30:02
TETRANDRINI DIMETHIODIDUM Chemical Properties,Uses,Production
Uses
Neuromuscular blocking agent.
General Description
Metocurine iodide, ( )-O,O -dimethylchondrocurarine diiodide (Metubine iodide),is prepared from natural crude curare by extracting the curarewith methanolic potassium hydroxide. When theextract is treated with an excess of methyl iodide, the ( )-tubocurarine is converted to the diquaternary dimethylether and crystallizes out as the iodide (see “TubocurarineChloride”). Other ethers besides the dimethyl ether havebeen made and tested. For example, the dibenzyl ether wasone third as active as tubocurarine chloride, and the diisopropylcompound had only one half the activity. For comparison,the dimethyl ether has approximately 4 times theactivity of tubocurarine chloride.
The pharmacological action of this compound is the sameas that of tubocurarine chloride, namely, a nondepolarizingcompetitive blocking effect on the motor end plate of skeletalmuscles. It is considerably more potent than d-tubocurarine,however, and has the added advantage of exerting much lesseffect on respiration. The effect on respiration is not a significantfactor in therapeutic doses. Accidental overdosage iscounteracted best by forced respiration.
TETRANDRINI DIMETHIODIDUM Preparation Products And Raw materials
TETRANDRINI DIMETHIODIDUM Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3878 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9343 | 55 | Inquiry |
| BOSCHE SCIENTIFIC, LLC | 732 565 9988 | United States | 6486 | 55 | Inquiry |
| ChemPacific Corporation | 410 633 5771 | United States | 6902 | 51 | Inquiry |
| APAC Pharmaceutical, LLC | +1(410) 997 5552 | United States | 6332 | 38 | Inquiry |
| kemikalieimport | + 45 - 2034 3359 | Europe | 6699 | 47 | Inquiry |
| ecochem international chemical broker | +45 45 42 34 36 | Europe | 6385 | 66 | Inquiry |
| 3B Scientific Corporation | 847.281.9822 | United States | 6744 | 47 | Inquiry |
| 2A PharmaChem USA | (630) 737-0988 | United States | 6148 | 39 | Inquiry |
| UK GREEN SCIENTIFIC CO.,LIMITED | +44(0)870 432 4488 | United Kingdom | 6107 | 47 | Inquiry |
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