NORBORMIDE

NORBORMIDE Structure
CAS No.
991-42-4
Chemical Name:
NORBORMIDE
Synonyms
s6999;Shoxin;mcn1025;s-6,999;raticide;Raticate;ent51,762;nobormide;mcneil1025;NORBORMIDE
CBNumber:
CB2693460
Molecular Formula:
C33H25N3O3
Molecular Weight:
511.57
MOL File:
991-42-4.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:14:08

NORBORMIDE Properties

Melting point 190-198°
Boiling point 598.31°C (rough estimate)
Density 1.2065 (rough estimate)
refractive index 1.7800 (estimate)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Solid
color Crystals
Water Solubility 60mg/L(room temperature)
Stability Light Sensitive
EPA Substance Registry System Norbormide (991-42-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
RIDADR  2588
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 in rats (mg/kg): 5.3 orally; 0.65 i.v. (Roszkowski)

NORBORMIDE Chemical Properties,Uses,Production

Description

Norbormide was first introduced on the market in 1964 as a selective raticide, but does not have a current registration for commercial use in the European Union or North America. Current use as a pesticide is minimal to nonexistent worldwide. This compound’s toxicity is highly specific for rats.

Chemical Properties

White solid. Insoluble in water; soluble in dilute acids.

Uses

Norbormide is used as a rodenticide. It acts as a vasoconstrictor and calcium channel blocker, but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.

Definition

A rodenticide specific for rats, supposedly nontoxic to other animals or to humans .

General Description

Colorless to off-white crystalline powder. Used as a selective rat poison.

Reactivity Profile

When heated to decomposition, NORBORMIDE emits toxic fumes of nitrogen oxides. Avoid alkalis. [EPA, 1998].

Hazard

Toxic by ingestion.

Health Hazard

Moderately to highly toxic to humans. Probable human lethal dose is 50 to 500 mg/kg, or 1 teaspoon to 1 pint for a 150 lb. person.

Fire Hazard

When heated to decomposition, NORBORMIDE emits toxic fumes of nitrogen oxides. Avoid alkalies.

Safety Profile

Poison by ingestion andintravenous routes. A rodenticide. When heated todecomposition it emits toxic fumes of NOx.

Potential Exposure

This material is used as a selective, fast acting rat poison.

Environmental Fate

Because of its use as a rodenticide, norbormide may have entered the environment, particularly as a soil contaminant. The vapor pressure for norbormide is estimated to be 4.3 ×10-22 mmHg at 25 ℃, while Henry’s constant is 2.7 × 10-23 atmm3 mol-1. Therefore, volatilization from wet or dry soil is not likely to occur. If present in contaminated soil, norbormide may be transported in the air and undergo wet or dry deposition. Also, with a Koc of 2000, there would be some minor soil mobility. The high Koc coupled with a bioconcentration factor (BCF) of 290 predicts that norbormide contaminating aquatic systems would adsorb to suspended solids or sediments and would bioconcentrate.

Shipping

UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).

Waste Disposal

Small amounts may be treated with alkali, then landfilled. Large amounts should be incinerated . In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

NORBORMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 29)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21667 55 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10311 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 23048 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong Zhonghe Chemical New Materials Co., Ltd 13003551299 13003551299 China 7567 58 Inquiry
LGC Science (Shanghai) Ltd. 17717235263 China 11677 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23980 58 Inquiry
Crescent Chemical Co., Inc. 631 348 0333 United States 4599 68 Inquiry
Raticate NORBORMIDE 4,7-methano-1h-isoindole-1,3(2h)-dione,3a,4,7,7a-tetrahydro-5-(hydroxyphenyl-2 a-2-pyridylbenzylidene)- compounds-6,999 ent51,762 mcn1025 mcneil1025 nobormide -pyridinylmethyl)-8-(phenyl-2-pyridinylmethylene)- raticide s-6,999 s6999 nobormide (f-iso) norbormide ((e-iso,ansi) norbormide (ISO) 5-(α-hydroxy-α-2-pyridylbenzyl)-7-(α-2-pyridylbenzylidene)bicyclo [2.2.1] hept-5-ene-2,3-dicarboximide 3a,4,7,7a-Tetrahydro-5-(hydroxyphenyl-2-pyridinylmethyl)-7-(phenyl-2-pyridinylmethylene)-4,7-methano-1H-isoindole-1,3(2H)-dione Shoxin 5-(α-hydroxy-α-2-pyridylbenzyl)-7-(α-2-pyridylbenzylidene)-5-norbornene-2,3-dicarboximide DNTHHIVFNQZZRD-UHFFFAOYSA-N 4,7-Methano-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-5-(hydroxyphenyl-2-pyridinylmethyl)-8-(phenyl-2-pyridinylmethylene)- 991-42-4 C33H25N3O3