DECANOIC-2,2-D2 ACID
- CAS No.
- 62716-49-8
- Chemical Name:
- DECANOIC-2,2-D2 ACID
- Synonyms
- Decanoic Acid-d2;Decanoic-d2 Acid;DECANOIC-2,2-D2 ACID
- CBNumber:
- CB2696870
- Molecular Formula:
- C10H18D2O2
- Molecular Weight:
- 174.28
- MOL File:
- 62716-49-8.mol
- Modify Date:
- 2023/7/7 8:28:07
DECANOIC-2,2-D2 ACID Chemical Properties,Uses,Production
Description
Decanoic acid-d2 is intended for use as an internal standard for the quantification of decanoic acid by GC- or LC-MS. Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC50 = 0.52 mM) over those expressing GluA1 (IC50 = 2.09 mM) or GluA1 and GluA2 subunits (IC50 = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M2 muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer.
Uses
Decanoic-2,2-d2 Acid (CAS# 62716-49-8) is a useful isotopically labeled research compound.
DECANOIC-2,2-D2 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
DECANOIC-2,2-D2 ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 02584622273; | China | 3022 | 58 | Inquiry |
| C/D/N Isotopes Inc. | 800 565 4696 | Canada | 4399 | 68 | Inquiry |
| Kanto Chemical Co., Inc. | +81 3 3663 7631 | Japan | 6762 | 74 | Inquiry |
| Medical Isotopes | 1-(603) 635-1722 | United States | 6185 | 68 | Inquiry |
| INDOFINE Chemical Company, Inc. | 1 888 463 6346 | United States | 6177 | 69 | Inquiry |
| Leancare Ltd. | +33 962096793 | United Kingdom | 6460 | 42 | Inquiry |
| Shanghai Xiyuan Biotechnology Co., Ltd | 021-58116080 | CHINA | 6936 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| Manhag Testing Technology Co., Ltd | 020-020-3846236 17688849268 | China | 7775 | 58 | Inquiry |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | China | 11289 | 58 | Inquiry |
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