DECANOIC-D19 ACID
- CAS No.
- 88170-22-3
- Chemical Name:
- DECANOIC-D19 ACID
- Synonyms
- DECANOIC-D19 ACID;capric acid-d19,oh;DECANOIC ACID (D19);DECANOIC-D19 ACID, 98 ATOM % D
- CBNumber:
- CB4346645
- Molecular Formula:
- C10HD19O2
- Molecular Weight:
- 191.38
- MOL File:
- 88170-22-3.mol
- Modify Date:
- 2023/6/8 9:03:00
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
DECANOIC-D19 ACID Chemical Properties,Uses,Production
Description
Decanoic acid-d19 is intended for use as an internal standard for the quantification of decanoic acid by GC- or LC-MS. Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC50 = 0.52 mM) over those expressing GluA1 (IC50 = 2.09 mM) or GluA1 and GluA2 subunits (IC50 = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M2 muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer.
Uses
Decanoic-d19 Acid is used on platinum-on-carbon-catalyzed multiple deuterium labeling of saturated fatty acids. Cylindrocyclophane biosynthesis involves functionalization of an unactivated carbon center.
DECANOIC-D19 ACID Preparation Products And Raw materials
DECANOIC-D19 ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| LGC Standards | +44 (0)20 8943 8480 | United Kingdom | 6495 | 0 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12584 | 58 | Inquiry |
| Shanghai wechem chemical co., ltd | 18824865657 | China | 498 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 40857 | 58 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 19921389125 19921389125 | China | 12065 | 58 | Inquiry |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | China | 5359 | 58 | Inquiry |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | China | 18488 | 58 | Inquiry |
| Aikon International Limited | 18626450290 | China | 10718 | 58 | Inquiry |