LAMININ
- CAS No.
- 114956-81-9
- Chemical Name:
- LAMININ
- Synonyms
- LAMININ;laminin, LN;LN, Human laminin;LAMININ, HUMAN PLACENTA;laminin from human placenta;Laminin from human fibroblasts ;cell culture derived, liquid, sterile-filtered;LAMININ FROM HUMAN PLACENTA CELL*CULTURE TESTED;laminin from engelbreth-holm-swarm murine sarcoma basement membrane;LAMININ FROM BASEMENT MEMBRANE OF ENGELBRETH HOLM-SWARM TRANSPLANTABLE MOUSE TUMOR
- CBNumber:
- CB2711739
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2023/4/23 13:52:06
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | B,Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
LAMININ price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | L6274 | Laminin from human placenta liquid, BioReagent, suitable for cell culture | 114956-81-9 | 0.5MG | ₹76957.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L2020 | Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane 1-2?mg/mL in Tris-buffered saline, 0.2 μm filtered, BioReagent, suitable for cell culture | 114956-81-9 | 1MG | ₹24229.2 | 2022-06-14 | Buy |
LAMININ Chemical Properties,Uses,Production
Uses
Laminin from human fibroblasts has been used:
- in coating six-well plates for wound healing assay
- as a substrate in cell adhesion and spreading assay
- for differentiation of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) toward dopaminergic neurons
- in corneal endothelial cell wound healing (migration) assay and corneal endothelial cell barrier assay
Laminin from human fibroblasts is recommended for use as a cell culture substratum at 1-2 μg/cm2. The optimal concentration does depend on cell type as well as the application or research objectives.
General Description
Laminin is purified as laminin-nidogen complex from mouse Engelbreth-Holm-Swarm (EHS) sarcoma. Laminin is a heterotrimer made from α, β and γ chain subunits. It is a glycoprotein which is required for the structural scaffolding of basement membranes. Laminin supports growth and differentiation of many cell types including epithelial, endothelial, neural, muscle and liver cells.
Biological activity: Tested for the promotion of adherence of HT-1080 cells.
Species specificity: Active on most mammalian cells.
Biochem/physiol Actions
Laminin proteins are integral components of structural scaffolding in animal tissues. They associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystroglycan glycoprotein complexes and Lutheran blood group glycoproteins. Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment.
LAMININ Preparation Products And Raw materials
Raw materials
Preparation Products
LAMININ Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
BIOTREND Chemikalien GmbH | 49 (0) 221 949 83 20 | Germany | 6115 | 76 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |
MP Biomedicals, Inc. | 949 833 2500 | United States | 6566 | 81 | Inquiry |
Roche Applied Science | 800 428 5433 | United States | 696 | 85 | Inquiry |
Upstate | 434 975 4300 | United States | 876 | 76 | Inquiry |
Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |
Beijing Hassanal Technology Limited Liability Company | 010-8293620852266225 | China | 750 | 43 | Inquiry |
Sinus Biochemistry & Electrophoresis GmbH | 0049 6221 82822 0 | Germany | 621 | 68 | Inquiry |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | China | 15848 | 69 | Inquiry |
Nanjing Peptide Biotech Ltd. | 025-025-58361106-805-805 13082558573 | China | 9978 | 55 | Inquiry |
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