AMI-193

AMI-193 Structure
CAS No.
510-74-7
Chemical Name:
AMI-193
Synonyms
R 5808;AMI-193;spiramide;Fluroxyspiramine;8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]-DECANONE;8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE;1-Phenyl-8-[3-(4-fluorophenoxy)propyl]-1,3,8-triazaspiro[4.5]decane-4-one;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-
CBNumber:
CB2728009
Molecular Formula:
C22H26FN3O2
Molecular Weight:
383.46
MOL File:
510-74-7.mol
Modify Date:
2023/9/4 15:51:00

AMI-193 Properties

Melting point 176 - 179°C
storage temp. Store at RT
solubility DMSO (Slightly), Methanol (Slightly)
form White solid.
color Off-White to Pale Yellow

AMI-193 Chemical Properties,Uses,Production

Definition

ChEBI: An azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spipero e but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour.

Biological Activity

Selective 5-HT antagonist, which binds to 5-HT 2 sites as potently as spiperone but has lower affinity for 5-HT 2C receptors. Also a high affinity D 2 receptor antagonist (K i = 3 nM). Lacks the disruptive effect of spiperone on animal behavior.

AMI-193 Preparation Products And Raw materials

Raw materials

Preparation Products

AMI-193 Suppliers

Global( 45)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 4088 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Chemtour Biotech Co., Ltd +8617327281506 China 1460 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 China 9929 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Suzhou Chenrui Biotechnology Co. LTD 17625585511 China 530 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry

AMI-193 Spectrum

8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE 8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]-DECANONE AMI-193 spiramide 1-Phenyl-8-[3-(4-fluorophenoxy)propyl]-1,3,8-triazaspiro[4.5]decane-4-one Fluroxyspiramine R 5808 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl- 510-74-7 C22H26FN3O2 Serotonin receptor