AMI-193

AMI-193 Structure
CAS No.
510-74-7
Chemical Name:
AMI-193
Synonyms
R 5808;AMI-193;spiramide;Fluroxyspiramine;AMI-193, 10 mM in DMSO;8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]-DECANONE;8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE;1-Phenyl-8-[3-(4-fluorophenoxy)propyl]-1,3,8-triazaspiro[4.5]decane-4-one;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-
CBNumber:
CB2728009
Molecular Formula:
C22H26FN3O2
Molecular Weight:
383.46
MOL File:
510-74-7.mol
Modify Date:
2025/4/17 18:22:24

AMI-193 Properties

Melting point 176 - 179°C
storage temp. Store at RT
solubility DMSO (Slightly), Methanol (Slightly)
form White solid.
color Off-White to Pale Yellow

AMI-193 Chemical Properties,Uses,Production

Definition

ChEBI: An azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spipero e but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour.

Biological Activity

Selective 5-HT antagonist, which binds to 5-HT 2 sites as potently as spiperone but has lower affinity for 5-HT 2C receptors. Also a high affinity D 2 receptor antagonist (K i = 3 nM). Lacks the disruptive effect of spiperone on animal behavior.

AMI-193 Preparation Products And Raw materials

Raw materials

Preparation Products

AMI-193 Suppliers

Global( 51)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 33024 60 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 3978 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32159 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3135 58 Inquiry
Chemtour Biotech Co., Ltd +8617327281506 China 1521 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +86-18621343501; +undefined18621343501 China 33338 58 Inquiry
Aladdin Scientific United States 57505 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40066 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9803 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24642 58 Inquiry

AMI-193 Spectrum

8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE 8-[3-(4-FLUOROPHENOXY)PROPYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]-DECANONE AMI-193 spiramide 1-Phenyl-8-[3-(4-fluorophenoxy)propyl]-1,3,8-triazaspiro[4.5]decane-4-one Fluroxyspiramine R 5808 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl- AMI-193, 10 mM in DMSO 510-74-7 C22H26FN3O2 Serotonin receptor