D-(+)-NEOPTERIN

CAS No.: 2009-64-5

Chemical Name:: D-(+)-NEOPTERIN

Synonyms: NEOPTERIN;(+)-NEOPTERIN;D-erythro-Form;2-Amino-6-((1S;D-(+)-NEOPTERIN;Neopterin (7CI);D(+)-Neopterin,99%;D-ERYTHRO-NEOPTERIN;D-(PLUS)-NEOPTERINE;D(+)-Neopterin, 99% 10MG

CBNumber:: CB2734079

Molecular Formula:: C9H11N5O4

Molecular Weight:: 253.21

MOL File:: 2009-64-5.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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D-(+)-NEOPTERIN Properties

Melting point	>232°C (dec.)
alpha	D25 +45 ± 3° (c = 0.3 in 0.1N HCl)
Boiling point	396.41°C (rough estimate)
Density	1.3957 (rough estimate)
refractive index	1.7610 (estimate)
storage temp.	2-8°C
solubility	Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly)
form	Off-white to yellow solid.
pka	12.60±0.20(Predicted)
color	Light Orange to Light Brown
Merck	13,6490
BRN	89070
Stability	Hygroscopic
InChIKey	BMQYVXCPAOLZOK-XINAWCOVSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

WGK Germany

HS Code

29335990

NFPA 704

	0
2		0

D-(+)-NEOPTERIN price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	N3386	D-(+)-Neopterin ≥97.5% (sum of enantiomers, HPLC)	2009-64-5	10MG	₹4503.2	2022-06-14	Buy
Sigma-Aldrich(India)	N3386	D-(+)-Neopterin ≥97.5% (sum of enantiomers, HPLC)	2009-64-5	25MG	₹10976.55	2022-06-14	Buy
Sigma-Aldrich(India)	N3386	D-(+)-Neopterin ≥97.5% (sum of enantiomers, HPLC)	2009-64-5	100MG	₹27300.65	2022-06-14	Buy

Product number	Packaging	Price	Buy
N3386	10MG	₹4503.2	Buy
N3386	25MG	₹10976.55	Buy
N3386	100MG	₹27300.65	Buy

D-(+)-NEOPTERIN Chemical Properties,Uses,Production

Description

Neopterin is a pyrazino-pyrimidine compound derived from GTP that represents an intermediate product in the synthetic pathway of biopterin and is an essential cofactor in neurotransmitter synthesis. Neopterin is released from macrophages upon immune stimulation with interferon-γ from activated T cells. It is routinely used as a biochemical tool to screen for and monitor the progression of certain diseases accompanied by hyperimmune stimulation.

Chemical Properties

off-white to yellow solid

Uses

D-(+)-Neopterin has been used as a NADPH oxidase inhibitor while assessing the ability of NADPH oxidases in breast cancer cells to produce reactive oxygen species (ROS). [NADPH= nicotinamide adenine dinucleotide phosphate]

General Description

D-(+)-Neopterin is a pteridine derivative, naturally found in Dictyostelium discoideum. It is found in significant amounts in the urine of cancer patients.

Purification Methods

Purification is as for biopterin. Also purify it on a Dowex-1 x 8 (formate form) column and elute with 0.03M ammonium formate buffer pH 8.0 then pH 7.2. The fluorescent neopterin fraction is evaporated under reduced pressure, leaving neopterin and ammonium formate (the latter sublimes out at high vacuum) behind. Stir the residue for 24hours with EtOH, collect the solid and recrystallise it from H2O. [Viscontini et al. Helv Chim Acta 53 1202 1970, cf Wachter et al. Eds Neopterin W de Gruyter, Berlin 1992, ISBN 9783110117905, Beilstein 26 IV 4038.]

D-(+)-NEOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

D-(+)-NEOPTERIN Suppliers

Global( 109)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	12962	58	Inquiry
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shaanxi kelkai Pharmaceutical Technology Co., Ltd	029-029-2148545164 17392779578	China	6640	58	Inquiry
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-400-6206333 18521732826	China	25014	65	Inquiry
Shanghai Yingxin Laboratory Equipment Co., Ltd.	021-021-59178156 17002132182	China	11609	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58
BOC Sciences	58
Zhengzhou Alfa Chemical Co.,Ltd	58
AFINE CHEMICALS LIMITED	58
LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Shaanxi kelkai Pharmaceutical Technology Co., Ltd	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Shanghai Yingxin Laboratory Equipment Co., Ltd.	58

2009-64-5(D-(+)-NEOPTERIN)Related Search:

Pyrazine ANTI-NEOPTERIN (6R)-Heptaacetyl-5-ethyl-5,6,7,8-tetrahydro-D-neopterin NEOPTERIN NEOPTERIN ELISA KIT 96 WELLS

NEOPTERIN, 7,8-DIHYDRO-D,7,8-DIHYDRO-D-NEOPTERIN (-)-L-Neopterin,L-Neopterin,L-erythro-Neopterin neopterin-3'-triphosphate 4-HYDROXYPTERIDINE 2-Pyrazinylmethanol

2-Propylpyrazine 2-(2'-HYDROXYETHYL)PYRAZINE D-(+)-NEOPTERIN Neopterin

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1-(2-amino-4-hydroxy-pteridin-6-yl)propane-1,2,3-triol 2-Amino-6-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(1H)-one D(+)-Neopterin,99% D(+)-Neopterin, 99% 10MG 2-AMino-6-[(1S,2R)-1,2,3-trihydroxypropyl]- D-(+)-Neopterin >=97.5% (suM of enantioMers, HPLC) D-erythro-Form (+)-NEOPTERIN NEOPTERIN D-(+)-NEOPTERIN D(+)-6-(ERYTHRO-1,2,3-TRIHYDROXYPROPYL)PTERIN D-ERYTHRO-NEOPTERIN [S-(R*,S*)]-2-amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-one D-(PLUS)-NEOPTERINE D-Neopterin [D-erythro-Neopterin] 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one 4(3H)-Pteridinone, 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]- 2-Amino-6-((1S 3-trihydroxypropyl)pteridin-4(3H)-one 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone Neopterin (7CI) inhibit,Endogenous Metabolite,Inhibitor,Neopterin Sapropterin Impurity 22 (D-Neopterin) 2009-64-5 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Others Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides Pharmaceuticals