3,3'-Dithiobis(sulfosuccinimidylpropionate)
![3,3'-Dithiobis(sulfosuccinimidylpropionate) Structure](CAS/GIF/81069-02-5.gif)
- CAS No.
- 81069-02-5
- Chemical Name:
- 3,3'-Dithiobis(sulfosuccinimidylpropionate)
- Synonyms
- DTSSP Crosslinker;3,3'-Dithiobis(sulfosuccinimidylpropionate);3,3'-Dithiobis(sulfosuccinimidylpropionate);DTSSP 3,3'-Dithiobis(sulfosucciniMidylpropionate);DTSSP 3,3'-Dithiobis(sulfosuccinimidylpropionate);3,3Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester;3,3'-Dithiobispropionic acid bis-sulfosuccinimidyl ester;3,3’-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester 90%;3,3`-Dithiobis(sulfosucciniMidylpropionate)(DTSSP(Sulfo-DSP));ADC Linkers,Inhibitor,inhibit,DTSSP Crosslinker,Antibody-drug conjugates linkers
- CBNumber:
- CB31073260
- Molecular Formula:
- C14H16N2O14S4
- Molecular Weight:
- 564.54
- MOL File:
- 81069-02-5.mol
- Modify Date:
- 2023/5/4 15:14:15
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H319-H315-H335 |
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Safety Statements | 26-36 |
HS Code | 29309090 |
3,3'-Dithiobis(sulfosuccinimidylpropionate) Chemical Properties,Uses,Production
Chemical Properties
12.0
Uses
It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent.
General Description
DTSSP is 3,3′-Dithiobis(sulfosuccinimidylpropionate), which contains an amine-reactive N-hydroxysulfosuccinimide (sulfo-NHS) ester at each end of an 8-carbon spacer arm. Sulfo-NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysulfosuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for sulfo-NHS-ester crosslinking reagents. DSS, the non-sulfonated analog of DTSSP is also available for applications that require a membrane-permeable crosslinker.
3,3'-Dithiobis(sulfosuccinimidylpropionate) Preparation Products And Raw materials
Raw materials
Preparation Products
3,3'-Dithiobis(sulfosuccinimidylpropionate) Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | China | 9322 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | China | 7431 | 58 | Inquiry |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Suzhou ARTK Medchem Co., Ltd. | +8618168183658 | China | 39009 | 58 | Inquiry |