TERT-BUTYL TRIMETHYLSILYLACETATE
- CAS No.
- 41108-81-0
- Chemical Name:
- TERT-BUTYL TRIMETHYLSILYLACETATE
- Synonyms
- Einecs 255-222-2;t-Butyl Trimethylsilylacetate;TERT-BUTYL TRIMETHYLSILYLACETATE;tert-butyl 2-trimethylsilylacetate;1,1-dimethylethyl trimethylsilylacetate;(Trimethylsilyl)acetic acid 1,1-dimethylethyl ester;Acetic acid, 2-(trimethylsilyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB3110801
- Molecular Formula:
- C9H20O2Si
- Molecular Weight:
- 188.34
- MOL File:
- 41108-81-0.mol
- Modify Date:
- 2023/5/15 10:43:57
TERT-BUTYL TRIMETHYLSILYLACETATE Chemical Properties,Uses,Production
Physical properties
air stable, colorless liquid; bp 67°C/13 mmHg; n20 D 1.4184; 1H NMR (CDCl3, 90 MHz) 0.13 (s, 9H), 1.45 (s, 9H), 1.80 (s, 2H); IR 1710 cm?1.
Uses
t-Butyl Trimethylsilylacetate is used to prepare lithium enolates which can be alkylated;can
be alkenated with aldehydes and ketones;can be acylated;can
be reacted with Group 14 halides.
Most applications require initial formation
of the enolate (1) (eq 1), which is obtained as a white solid suspended
in THF, stable indefinitely at ?78°C.
Preparation
an advantage of t-butyl trimethylsilylacetate over its methyl and ethyl ester analogs is that it can be prepared by C-silylation of the lithium enolate of t-butyl acetate at ?78°C in THF (85–90% yield). Under the same conditions the enolates of methyl and ethyl acetate give primarily O-silylated products.The reagent has also been prepared by a rapid boron trifluoride etherate catalyzed reaction of trimethylsilylketene with t-butyl alcohol.
TERT-BUTYL TRIMETHYLSILYLACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16917 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9335 | 55 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30251 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| CD Chemical Group Limited | +8615986615575 | China | 20356 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | China | 10010 | 58 | Inquiry |
| United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
| Sigma-Aldrich | 021-61415566 800-8193336 | China | 51471 | 80 | Inquiry |