brusatol
![brusatol Structure](CAS/GIF/14907-98-3.gif)
- CAS No.
- 14907-98-3
- Chemical Name:
- brusatol
- Synonyms
- 100935;Brustaol;Yatansin;Brusato1;NSC 172924;(+)-Brusatol;Brusatol >=95% (HPLC);Brusatol (NSC 172924);Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-;13,20-Epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicras-3-en-21-oic acid methyl ester
- CBNumber:
- CB31342731
- Molecular Formula:
- C26H32O11
- Molecular Weight:
- 520.53
- MOL File:
- 14907-98-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/8 16:27:35
Boiling point | 724.3±60.0 °C(Predicted) |
---|---|
Density | 1.46±0.1 g/cm3 (20 ºC 760 Torr) |
storage temp. | -20°C |
solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
pka | 8.81±0.70(Predicted) |
form | powder |
color | white to beige |
optical activity | [α]/D +35 to +44°, c = 0.5 in acetone |
LogP | 0.393 (est) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
brusatol price More Price(2)
brusatol Chemical Properties,Uses,Production
Uses
Brusatol has been used to study the protective role of Nrf2 (nuclear factor, erythroid 2 like 2 ) in intestinal ischemia/reperfusion induced injury.
Biochem/physiol Actions
Brusatol promotes Nrf2 (nuclear factor, erythroid 2 like 2 ) ubiquitination and degradation. Brusatol upregulates the expression of multiple ribosomal components and controls macromolecular complex function.
brusatol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 144)Suppliers
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14907-98-3(brusatol)Related Search:
bruceine D
bruceine A
(-)-13,20-Epoxy-1β,11β,12α,14,15β,21-hexahydroxypicrasa-3-ene-2,16-dione
yadanziolide A
bruceine B
YADANZIOLIDE-C
(+)-13,20-Epoxy-1β,6α,11β,12α,14,15β,21-heptahydroxypicrasa-3-ene-2,16-dione
YADANZIOSIDE-L
Methyl 2-tetrahydrofuroate
Tetrahydropyranyl-4-acetic acid
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13,20-Epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicras-3-en-21-oic acid methyl ester
13,20-Epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicrasa-3-ene-21-oic acid methyl ester
Picras-3-en-21-oicacid,13,20-epoxy-3,11,12-trihydroxy-15-[(3-Methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-,Methyl ester, (11b,12a,15b)-
NSC 172924
Yatansin
Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-
Brustaol
Brusatol (NSC 172924)
(1R,2S,3S,3aS,3a1R,4R,6aR,7aR,11aS,11bR)-Methyl 1,2,9-trihydroxy-8,11a-dimethyl-4-((3-methylbut-2-enoyl)oxy)-5,10-dioxo-2,3,3a,4,5,6a,7,7a,10,11,11a,11b-dodecahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromene-3-carboxylate
(+)-Brusatol
Brusatol >=95% (HPLC)
Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-, methyl ester, (11β,12α,15β)-
Brusato1
100935
methyl (1R,2S,3S,3aS,3a1R,4R,6aR,7aR,11aS,11bR)-1,2,9-trihydroxy-8,11a-dimethyl-4-((3-methylbut-2-enoyl)oxy)-5,10-dioxo-1,4,5,6a,7,7a,10,11,11a,11b-decahydro-2H-3,3a1-(epoxymethano)dibenzo[de,g]chromene-3(3aH)-carboxylate
14907-98-3