monazomycin

monazomycin Structure
CAS No.
11006-31-8
Chemical Name:
monazomycin
Synonyms
monazomycin;Monazomycin DISCONTINUED;Oxacyclooctatetraconta-13,17,21,29-tetraen-2-one, 48-(7-amino-1-methylheptyl)-8,10,16,20,24,26,28,32,36,38,40,42,44,46-tetradecahydroxy-23-(α-D-mannopyranosyloxy)-9,15,17,19,21,25,31,33,39,41,47-undecamethyl-
CBNumber:
CB31349624
Molecular Formula:
C72H133NO22
Molecular Weight:
1364.82
MOL File:
11006-31-8.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

monazomycin Properties

Melting point 127°C
Boiling point 866.56°C (rough estimate)
Density 0.9708 (rough estimate)
refractive index 1.5280 (estimate)
storage temp. Store at -20°C
solubility Soluble in DMSO
form solid
pka 12.89±0.70(Predicted)

monazomycin Chemical Properties,Uses,Production

Uses

Monazomycin is a macrocylic polyol lactone isolated from several species of Streptoverticillium, first reported in 1963. Monazomycin is active against Gram positive bacteria with weak Gram negative activity. In solution, monazomycin exists as hydrophilic clusters which, when adsorbed onto a lipid bilayer, can induce channel formation. Monazomycin is an important bioprobe for understanding membrane channels.

monazomycin Preparation Products And Raw materials

Raw materials

Preparation Products

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monazomycin Oxacyclooctatetraconta-13,17,21,29-tetraen-2-one, 48-(7-amino-1-methylheptyl)-8,10,16,20,24,26,28,32,36,38,40,42,44,46-tetradecahydroxy-23-(α-D-mannopyranosyloxy)-9,15,17,19,21,25,31,33,39,41,47-undecamethyl- Monazomycin DISCONTINUED 11006-31-8 C72H133NO22