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ALPHA-AMANITIN

ALPHA-AMANITIN Structure
CAS No.
23109-05-9
Chemical Name:
ALPHA-AMANITIN
Synonyms
Α-AMANITIN;α-Amanitin;A-AMANITIN;Aids004473;α-Amatoxin;Aids-004473;AMANITIN, A-;ALPHA-AMANTIN;ALPHA-AMANITIN;alpha-amatoxin
CBNumber:
CB3142945
Molecular Formula:
C39H54N10O14S
Molecular Weight:
918.98
MOL File:
23109-05-9.mol
MSDS File:
SDS
Modify Date:
2024/5/16 15:51:48

ALPHA-AMANITIN Properties

Melting point 254-255 °C(lit.)
alpha D20 +191°
Boiling point 1622.2±65.0 °C(Predicted)
Density 1.1626 (rough estimate)
refractive index 1.7400 (estimate)
storage temp. −20°C
solubility H2O: 1.0 mg/mL
form powder
pka 9.63±0.70(Predicted)
color white to light yellow
Water Solubility Soluble to 5 mM in ethanol and to 5 mM in water
Merck 13,370
BRN 1071138
InChIKey CIORWBWIBBPXCG-PWKRRBCNNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H373
Precautionary statements  P260-P264-P270-P301+P310-P314-P405
Hazard Codes  T+
Risk Statements  26/27/28-33-26/28
Safety Statements  36/37/39-45-36/37-28
RIDADR  UN 3462 6.1/PG 2
WGK Germany  3
RTECS  BD6195000
8-10-18-21
HazardClass  6.1(a)
PackingGroup  I
HS Code  2934999090
Toxicity LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland)
NFPA 704
0
4 0

ALPHA-AMANITIN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A2263 α-Amanitin from Amanita phalloides, ≥85% (HPLC), powder 23109-05-9 1MG ₹32290.98 2022-06-14 Buy
Product number Packaging Price Buy
A2263 1MG ₹32290.98 Buy

ALPHA-AMANITIN Chemical Properties,Uses,Production

Uses

α-Amanitin has been used:

  • for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay
  • to induce nephrotoxicity in mice renal tissues
  • to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay

Biochem/physiol Actions

The major toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but does not inhibit RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.

ALPHA-AMANITIN Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-AMANITIN Suppliers

Global( 106)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Hebei Kangcang new material Technology Co., LTD +8615713292910 China 341 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29894 58 Inquiry
Dorne Chemical Technology co. LTD +86-86-13583358881 +8618560316533 China 3145 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
ChemExpress +86-021-58950125 +86-021-58950125; China 598 58 Inquiry
Hebei baicao biology science and technology co., ltd +86-19131911055 +8617824879454 China 1035 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
guoyungurui 18162595016 China 10337 58 Inquiry
Aids004473 Aids-004473 AMANITIN, a-(RG) AMANITIN, a-(RG)(CALL) cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4-8)-sulfide(R)-S-oxide alpha-AMantine, froM AManita Phalloides AMANITIN, A- ALPHA-AMANITIN ALPHA-AMANITIN, AMANITA SPECIES ALPHA-AMANITINE Cyclo[L-Asn-L-t4Hyp-[(3R,4R)-4,5-dihydroxy-3-methyl-L-Nva-]-6-hydroxy-L-Trp2(1)-Gly-3-methyl-L-Nva-Gly-3-oxomercapto(1)-L-Ala-] alpha-amatoxin cyclic(l-asparaginyl-4-hydroxy-l-prolyl-(r)-4,5-dihydroxy-l-isoleucyl-6-hydrox ulfide,(r)-s-oxide y-2-mercapto-l-tryptophylglycyl-l-isoleucylglycyl-l-cysteinyl),cyclic(4-8)-s ALPHA-AMANITIN FROM AMANITA PHALLOIDES A-AMANITIN FROM AMANITA PHALLOIDES ALPHA-AMANTIN ALPHA-AMANTINE A-AMANTINE, FROM AMANITA PHALLOIDES alpha-Amanitine, from Amanita Phalloides Α-AMANITIN;Α-AMATOXIN alpha-Amanitin (α-Amanitin α-Amanitin DISCONTINUED α-Amanitin, from Amanita Phalloides Α-AMANITIN A-AMANITIN α-Amanitin α-Amatoxin *Chlorobutanol Impurity?1 (Chlorobutanol EP Impurity?A)(Chloroform) 23109-05-9 C39H54N10O14S BioChemical Biochemicals and Reagents Cell Biology Cell Signaling and Neuroscience Gene Regulation and Expression Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors DNA-RNA Transcription Regulators Other Alkaloids DNA-RNA Transcription RegulatorsCell Signaling and Neuroscience Gene Regulation and Expression Cell Signaling and Neuroscience Mushroom Toxins and Venoms Enzyme Inhibitors Enzyme Inhibitors by Type Other Miscellaneous Enzyme inhibitor