ALPHA-AMANITIN
![ALPHA-AMANITIN Structure](CAS/GIF/23109-05-9.gif)
- CAS No.
- 23109-05-9
- Chemical Name:
- ALPHA-AMANITIN
- Synonyms
- Α-AMANITIN;α-Amanitin;A-AMANITIN;Aids004473;α-Amatoxin;Aids-004473;AMANITIN, A-;ALPHA-AMANTIN;ALPHA-AMANITIN;alpha-amatoxin
- CBNumber:
- CB3142945
- Molecular Formula:
- C39H54N10O14S
- Molecular Weight:
- 918.98
- MOL File:
- 23109-05-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 15:51:48
Melting point | 254-255 °C(lit.) |
---|---|
alpha | D20 +191° |
Boiling point | 1622.2±65.0 °C(Predicted) |
Density | 1.1626 (rough estimate) |
refractive index | 1.7400 (estimate) |
storage temp. | −20°C |
solubility | H2O: 1.0 mg/mL |
form | powder |
pka | 9.63±0.70(Predicted) |
color | white to light yellow |
Water Solubility | Soluble to 5 mM in ethanol and to 5 mM in water |
Merck | 13,370 |
BRN | 1071138 |
InChIKey | CIORWBWIBBPXCG-PWKRRBCNNA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS06,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H300-H373 | |||||||||
Precautionary statements | P260-P264-P270-P301+P310-P314-P405 | |||||||||
Hazard Codes | T+ | |||||||||
Risk Statements | 26/27/28-33-26/28 | |||||||||
Safety Statements | 36/37/39-45-36/37-28 | |||||||||
RIDADR | UN 3462 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | BD6195000 | |||||||||
F | 8-10-18-21 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | I | |||||||||
HS Code | 2934999090 | |||||||||
Toxicity | LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland) | |||||||||
NFPA 704 |
|
ALPHA-AMANITIN Chemical Properties,Uses,Production
Uses
α-Amanitin has been used:
- for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay
- to induce nephrotoxicity in mice renal tissues
- to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay
Biochem/physiol Actions
The major toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but does not inhibit RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.
ALPHA-AMANITIN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA-AMANITIN Suppliers
Global( 106)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Hebei Kangcang new material Technology Co., LTD | +8615713292910 | China | 341 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29894 | 58 | Inquiry |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3145 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
ChemExpress | +86-021-58950125 +86-021-58950125; | China | 598 | 58 | Inquiry |
Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | China | 1035 | 58 | Inquiry |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
guoyungurui | 18162595016 | China | 10337 | 58 | Inquiry |
23109-05-9(ALPHA-AMANITIN)Related Search:
Aids004473
Aids-004473
AMANITIN, a-(RG)
AMANITIN, a-(RG)(CALL)
cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4-8)-sulfide(R)-S-oxide
alpha-AMantine, froM AManita Phalloides
AMANITIN, A-
ALPHA-AMANITIN
ALPHA-AMANITIN, AMANITA SPECIES
ALPHA-AMANITINE
Cyclo[L-Asn-L-t4Hyp-[(3R,4R)-4,5-dihydroxy-3-methyl-L-Nva-]-6-hydroxy-L-Trp2(1)-Gly-3-methyl-L-Nva-Gly-3-oxomercapto(1)-L-Ala-]
alpha-amatoxin
cyclic(l-asparaginyl-4-hydroxy-l-prolyl-(r)-4,5-dihydroxy-l-isoleucyl-6-hydrox
ulfide,(r)-s-oxide
y-2-mercapto-l-tryptophylglycyl-l-isoleucylglycyl-l-cysteinyl),cyclic(4-8)-s
ALPHA-AMANITIN FROM AMANITA PHALLOIDES
A-AMANITIN FROM AMANITA PHALLOIDES
ALPHA-AMANTIN
ALPHA-AMANTINE
A-AMANTINE, FROM AMANITA PHALLOIDES
alpha-Amanitine, from Amanita Phalloides
Α-AMANITIN;Α-AMATOXIN
alpha-Amanitin
(α-Amanitin
α-Amanitin
DISCONTINUED
α-Amanitin, from Amanita Phalloides
Α-AMANITIN
A-AMANITIN
α-Amanitin
α-Amatoxin
*Chlorobutanol Impurity?1 (Chlorobutanol EP Impurity?A)(Chloroform)
23109-05-9
C39H54N10O14S
BioChemical
Biochemicals and Reagents
Cell Biology
Cell Signaling and Neuroscience
Gene Regulation and Expression
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Type
Enzyme Inhibitors
DNA-RNA Transcription Regulators
Other
Alkaloids
DNA-RNA Transcription RegulatorsCell Signaling and Neuroscience
Gene Regulation and Expression
Cell Signaling and Neuroscience
Mushroom
Toxins and Venoms
Enzyme Inhibitors
Enzyme Inhibitors by Type
Other
Miscellaneous Enzyme
inhibitor