17ALPHA-HYDROXYPREGNENOLONE

17ALPHA-HYDROXYPREGNENOLONE Structure
CAS No.
387-79-1
Chemical Name:
17ALPHA-HYDROXYPREGNENOLONE
Synonyms
NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone
CBNumber:
CB3175435
Molecular Formula:
C21H32O3
Molecular Weight:
332.48
MOL File:
387-79-1.mol
Modify Date:
2024/11/14 20:10:21

17ALPHA-HYDROXYPREGNENOLONE Properties

Melting point 273℃
Flash point 9℃
storage temp. -20°C
solubility Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)
form Solid
Boiling point 478.4±45.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
pka 13.02±0.70(Predicted)
color White to Off-White
CAS DataBase Reference 387-79-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN1230 - class 3 - PG 2 - Methanol
WGK Germany  3
RTECS  TU5548000

17ALPHA-HYDROXYPREGNENOLONE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H5002 17α-Hydroxypregnenolone 387-79-1 5G ₹59115.33 2022-06-14 Buy
Sigma-Aldrich(India) H-105 17α-Hydroxypregnenolone solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 387-79-1 1ML ₹15374.8 2022-06-14 Buy
Product number Packaging Price Buy
H5002 5G ₹59115.33 Buy
H-105 1ML ₹15374.8 Buy

17ALPHA-HYDROXYPREGNENOLONE Chemical Properties,Uses,Production

Description

17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.

Uses

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

General Description

17α-hydroxypregnenolone is a derived from pregnenolone.

17ALPHA-HYDROXYPREGNENOLONE Suppliers

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17alpha-Hydroxy (3b)-3,17-dihydroxy-Pregn-5-en-20-one 17a-Hydroxypregnolone 17ALPHA-LPHA-HYDROXYPREGNENOLONE 5-Pregnen-3b,17-dihydroxy-3-one 3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one 17-OH PREG 17-OH Pregnenolone 3β,17-Dihydroxypregn-5-en-20-one 3β,17α-Dihydroxypregn-5-en-20-one 3-beta,17-dihydroxypregn-5-en-20-one 3-beta,17-alpha-dihydroxypregn-5-en-20-one Hydroxypregnenolone 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H ASSAY ASSAY CHARACTERISTICS 17ALPHA-LPHA-HYDROXYPREGNENOLONE (1,2-3 H) 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H RIA KIT ASSAY CHARACTERISTICS 17ALPHA-LPHA-HYDROXYPREGNENOLONE CRYSTALLINE 17α-Hydroxypregnenolone,3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one NSC 63853 3β,17α-Dihydroxy-5-pregnen-20-one 5-Pregnene-3β,17α-diol-20-one 17α-Hydroxypregnenolone solution 17α-hydroxypregnenolone solution,100ppm 3B 17A-DIHYDROXYPREGN-5-EN-20-ONE 3BETA,17ALPHA-DIHYDROXY-DELTA5-PREGNEN-20-ONE 3BETA,17ALPHA-DIHYDROXY-5-PREGNEN-20-ONE 3-BETA,17-DIHYDROXY-5-PREGNEN-3-ONE 5-PREGNENE-3BETA,17ALPHA-DIOL-20-ONE 5-PREGNEN-3-BETA, 17-DIOL-20-ONE 5-PREGNEN-3BETA-17A-DIOL-20-ONE 5-PREGNEN-3BETA,17ALPHA-DIOL-20-ONE 17-dihydroxy-(3-beta)-pregn-5-en-20-on 3-beta,17-dihydroxy-pregn-5-en-20-on HYDROXYPREGNENOLONE, 17A- 17A-HYDROXYPREGENOLONE 17A-HYDROXY PREGNENOLONE 17ALPHA-HYDROXYPREGNENOLONE 17-HYDROXYPREGNENOLONE Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)- 17alpha-Hydroxypregnenolone-20,21-13C2,16,16-d2 17α-Hydroxypregnenolone 3b,17-Dihydroxy-5-pregnen-20-one 17α-Hydroxypregnenolone (Solution) "17A-HYDROXY PREGNENOLONE 13C2,D2" Inhibitor,17a Hydroxypregnenolone,Endogenous Metabolite,17aHydroxypregnenolone,inhibit,17a-Hydroxypregnenolone Dronedarone HCl-d6 5-PREGNEN-3β, 17-DIOL-20-ONE 17α-Hydroxypregnenolone-[13C2,d2] in Methanol 17α-Hydroxypregnenolone in Methanol 387-79-1 Steroids