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4-N-BUTOXYBENZYL BROMIDE

4-N-BUTOXYBENZYL BROMIDE Structure
CAS No.
2417-74-5
Chemical Name:
4-N-BUTOXYBENZYL BROMIDE
Synonyms
4-BUTOXYBENZYL BROMIDE;4-N-BUTOXYBENZYL BROMIDE;Benzene, 1-(bromomethyl)-4-butoxy-
CBNumber:
CB3201228
Molecular Formula:
C11H15BrO
Molecular Weight:
243.14
MOL File:
2417-74-5.mol
Modify Date:
2023/4/27 16:27:43

4-N-BUTOXYBENZYL BROMIDE Chemical Properties,Uses,Production

Uses

4-N-BUTOXYBENZYL BROMIDE is an intermediate used to prepare 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines with antirhinovirus activity. It is also used in the synthesis of alkyl derivatives of the glycopeptide antibiotic A40926 and their amides with antibacterial acitivity.    

Synthesis

The synthesis of 4-N-BUTOXYBENZYL BROMIDE is as follows:Under the protection of nitrogen,Add 40g of compound 5-1 to a 1L reaction flask,50g hydrogen bromide solution (hydrogen bromide concentration is 40wt%) and 500mL toluene,After fully dissolving, control the temperature between 110130,The reaction was stirred for 5h.Add 300 mL of ethyl acetate and 400 mL of water to the reaction solution for extraction,Collect the ethyl acetate layer, add anhydrous sodium sulfate for drying, then concentrate,Obtain 40 g of white solid (compound 6-1),The yield was 74.12%.
synthesis of 4-N-BUTOXYBENZYL BROMIDE.png

4-N-BUTOXYBENZYL BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-N-BUTOXYBENZYL BROMIDE Suppliers

Global( 13)Suppliers
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Dhruvtara Chemicals Pvt. Ltd. 91 40 27154607 New Delhi, India 180 56 Inquiry
Dhruvtara Chemicals Private Limited 08048361362Ext 107 Hyderabad, India 84 58 Inquiry
Nanjing Triumpharm Co.,Ltd +86-02586182925 +86-15105172550 China 129 58 Inquiry
Nanjing Shengkai Pharmaceutical Technology Co., Ltd. 025-86182925 17749516701 China 154 58 Inquiry
Pushan Industry (Shaanxi) Co., Ltd 029-81310890 18165209495 China 10006 58 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
ecochem international chemical broker +45 45 42 34 36 Europe 6385 66 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
4-N-BUTOXYBENZYL BROMIDE 4-BUTOXYBENZYL BROMIDE Benzene, 1-(bromomethyl)-4-butoxy- 2417-74-5