4-N-BUTOXYBENZYL BROMIDE

- CAS No.
- 2417-74-5
- Chemical Name:
- 4-N-BUTOXYBENZYL BROMIDE
- Synonyms
- 4-BUTOXYBENZYL BROMIDE;4-N-BUTOXYBENZYL BROMIDE;Benzene, 1-(bromomethyl)-4-butoxy-
- CBNumber:
- CB3201228
- Molecular Formula:
- C11H15BrO
- Molecular Weight:
- 243.14
- MOL File:
- 2417-74-5.mol
- Modify Date:
- 2023/4/27 16:27:43
4-N-BUTOXYBENZYL BROMIDE Chemical Properties,Uses,Production
Uses
4-N-BUTOXYBENZYL BROMIDE is an intermediate used to prepare 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines with antirhinovirus activity. It is also used in the synthesis of alkyl derivatives of the glycopeptide antibiotic A40926 and their amides with antibacterial acitivity.
Synthesis
The synthesis of 4-N-BUTOXYBENZYL BROMIDE is as follows:Under the protection of nitrogen,Add 40g of compound 5-1 to a 1L reaction flask,50g hydrogen bromide solution (hydrogen bromide concentration is 40wt%) and 500mL toluene,After fully dissolving, control the temperature between 110130,The reaction was stirred for 5h.Add 300 mL of ethyl acetate and 400 mL of water to the reaction solution for extraction,Collect the ethyl acetate layer, add anhydrous sodium sulfate for drying, then concentrate,Obtain 40 g of white solid (compound 6-1),The yield was 74.12%.
4-N-BUTOXYBENZYL BROMIDE Preparation Products And Raw materials
4-N-BUTOXYBENZYL BROMIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Dhruvtara Chemicals Pvt. Ltd. | 91 40 27154607 | New Delhi, India | 180 | 56 | Inquiry |
Dhruvtara Chemicals Private Limited | 08048361362Ext 107 | Hyderabad, India | 84 | 58 | Inquiry |
Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 | China | 129 | 58 | Inquiry |
DAYANG CHEM (HANGZHOU) CO.,LTD | +8617705817739 | China | 53881 | 58 | Inquiry |
Nanjing Shengkai Pharmaceutical Technology Co., Ltd. | 025-86182925 17749516701 | China | 153 | 58 | Inquiry |
Pushan Industry (Shaanxi) Co., Ltd | 029-81310890 18165209495 | China | 9994 | 58 | Inquiry |
CHEMICAL LAND21 | 82- 2 -783 - 8063 | South Korea | 6303 | 74 | Inquiry |
kemikalieimport | + 45 - 2034 3359 | Europe | 6685 | 47 | Inquiry |
ecochem international chemical broker | +45 45 42 34 36 | Europe | 6371 | 66 | Inquiry |
Service Chemical Inc. | 888-895-6920 | Germany | 6350 | 71 | Inquiry |