5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Structure
CAS No.
28480-70-8
Chemical Name:
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
Synonyms
2-ACETYL-4-CHLORO-5-METHYLPHENOL;4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE;5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE;5'-Cloro-2'-Hydroxy-4'-Methylacetophenone;5'-Chooro-2'-Hydroxy-4'-Methylacetophenone;5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE;5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE;1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE;5'-Chloro-2'-hydroxy-4'-methylacetophenone 98%;5'-Chloro-2'-hydroxy-4'-methylacetophenone >
CBNumber:
CB3212213
Molecular Formula:
C9H9ClO2
Molecular Weight:
184.62
MOL File:
28480-70-8.mol
Modify Date:
2023/6/8 17:06:34

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Properties

Melting point 70-73 °C(lit.)
Boiling point 137 °C / 15mmHg
Density 1.250±0.06 g/cm3(Predicted)
pka 9.84±0.23(Predicted)
form powder to crystal
color White to Light yellow
CAS DataBase Reference 28480-70-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  2914.50.3000

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 415758 5′-Chloro-2′-hydroxy-4′-methylacetophenone 98% 28480-70-8 5G ₹5574.88 2022-06-14 Buy
TCI Chemicals (India) C1629 5'-Chloro-2'-hydroxy-4'-methylacetophenone min. 95.0 % 28480-70-8 5G ₹2800 2022-05-26 Buy
TCI Chemicals (India) C1629 5'-Chloro-2'-hydroxy-4'-methylacetophenone min. 95.0 % 28480-70-8 25G ₹8800 2022-05-26 Buy
Product number Packaging Price Buy
415758 5G ₹5574.88 Buy
C1629 5G ₹2800 Buy
C1629 25G ₹8800 Buy

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Chemical Properties,Uses,Production

Uses

5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:

  • chalcones, required for the synthesis of novel pyrazoline derivatives
  • 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
  • 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)

Preparation

Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%).

General Description

5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Preparation Products And Raw materials

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5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE 5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE 4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE 1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE 2-ACETYL-4-CHLORO-5-METHYLPHENOL 5'-Chooro-2'-Hydroxy-4'-Methylacetophenone 4-Acetyl-2-chloro-5-hydroxytoluene 2-Acetyl-4-chloro-5-methylphenol 5'-Chloro-2'-hydroxy-4'-methylacetophenone 98% JRH-01005, 1-(5-Chloro-2-hydroxy-4-methylphenyl)ethanone, 97% 5'-Chloro-2'-hydroxy-4'-methylacetophenone > Ethanone, 1-(5-chloro-2-hydroxy-4-methylphenyl)- 5'-Cloro-2'-Hydroxy-4'-Methylacetophenone 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE 28480-70-8 ClC6H2OHCH3COCH3 C9 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones Ketones Aromatic Acetophenones & Derivatives (substituted) C9 Carbonyl Compounds