Cloquintocet-mexyl
- CAS No.
- 99607-70-2
- Chemical Name:
- Cloquintocet-mexyl
- Synonyms
- Cloquintocet-1;oquintocet-MexyL;cloquitocet_mexyl;CLOQUINTOCET-MEXYL;Cloquintocet-methyl;Adagrasib Impurity 59;Cloquintocet-mexyl >Cloquintocet-mexyl Standard;99607-70-2 (CLOQUINTOCET-MEXYL);high quality Cloquintocet-mexyl
- CBNumber:
- CB3243431
- Molecular Formula:
- C18H22ClNO3
- Molecular Weight:
- 335.83
- MOL File:
- 99607-70-2.mol
- Modify Date:
- 2024/7/29 18:03:56
| Melting point | 69° |
|---|---|
| Boiling point | 448.4±30.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| vapor pressure | 0-54.4Pa at 25-185.9℃ |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 1.94±0.29(Predicted) |
| color | White to Off-White |
| Merck | 14,2401 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | 5.2-5.24 at 25℃ and pH5-9.1 |
| Surface tension | 56.8-57.2mN/m at 590μg/L and 20℃ |
| Dissociation constant | 3.55 at 20℃ |
| CAS DataBase Reference | 99607-70-2(CAS DataBase Reference) |
| EPA Substance Registry System | Cloquintocet-mexyl (99607-70-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H410 |
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| RIDADR | UN 3077 |
| WGK Germany | 2 |
| RTECS | AG1265000 |
| HS Code | 2933.49.3000 |
| Toxicity | LD50 in rats (mg/kg): >2000 orally; >2000 dermally; LC50 (4 hr) in rats: >935 mg/m3 by inhalation (Amrein) |
Cloquintocet-mexyl price More Price(2)
Cloquintocet-mexyl Chemical Properties,Uses,Production
Description
Cloquintocet-mexyl is a colourless crystalline herbicide safener. It is categorized as Class III toxin.
Chemical Properties
beige solid
Uses
Cloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired.
Agricultural Uses
Cloquintocet-mexyl is a safener that can be used in conjunction with various herbicides to reduce phytotoxicity to crops. Though effective as a safener, the manufacture, storage, and use of cloquintocet-mexyl containing products can present challenges owing to its sensitivity to water and its low melting temperature (i.e., 61-69° C. for technical material). When products containing cloquintocet-mexyl are prepared, stored, or used in the presence of water, cloquin tocet-mexyl can undergo hydrolysis to form cloquintocet acid, and/or form a needle-shaped, crystalline hydrate that can, lead to clogged spray nozzles during spray applications and/or possibly increased levels of crop phytotoxicity.
Carcinogenicity
In accordance with the EPA Proposed EPA Weight-of-the-Evidence Categories, August 1999, the HIARC classified cloquintocet-mexyl as "not likely to be a human carcinogen." Carcinogenicity studies in rats and mice did not show increased incidence of spontaneous tumor formation. With negative mutagenic test battery, it is suggested that cloquintocet-mexyl (CGA 185072) is not likely to be a human carcinogen.
Metabolism
Metabolism studies in rats indicated that approximately 40% of the administered dose of cloquintocet-mexyl was absorbed through the gastrointestinal tract and subsequently excreted via the urine. Fecal excretion accounted for approximately 60% of the administered dose. The chemical was rapidly eliminated (more than 80% of the administered dose) via feces and urine within 48 hours post-dosing. Sex, dosing regime, and dose levels had little effect on the excretion pattern. Excretion patterns were similar between the biliary cannulated and non-cannulated animals indicating that there was no enterohepatic circulation of the chemical. Three days after administration, tissue radioactivity accounted for less than 0.3% of the administered dose (or was non-detectable) and was not detectable in the expired air. At day three post-dosing, most tissue residues of radioactivity were below the limit of detection. The major metabolic pathway of cloquintocet-mexyl was ester hydrolysis to yield 5-chloro-8-quinolinoxy acetic acid, the major metabolite in the fecal and urinary pools.
Cloquintocet-mexyl Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
| United Phosphorus Limited | +91-2271528737 +91-9004390689 | Mumbai, India | 32 | 58 | Inquiry |
| Bharat Rasayan | +91-9619772584 +91-9619772584 | Maharashtra, India | 23 | 58 | Inquiry |
| Auro Pharmaceuticals And Fine Chemicals Pvt Ltd | +91-2024475340 +91-8087324189 | Maharashtra, India | 25 | 58 | Inquiry |
| Bhagiradha Chemicals And Industries Limited | +91-4042212323 +91-4042221212 | Telangana, India | 12 | 58 | Inquiry |
| HPM Chemicals And Fertilizers Ltd | +91-1145071800 +91-8275418788 | New Delhi, India | 13 | 58 | Inquiry |
| Shiva Pharmachem Pvt Ltd | +91-2652321418 +91-2652321418 | Gujarat, India | 64 | 58 | Inquiry |
| HPM Chemicals & Fertilizers Ltd. | 91-11-45071800 | Delhi, India | 4 | 58 | Inquiry |
| Bharat Rasayan Limited - BRL (Bharat Group) | 91-11-43661111 | Delhi, India | 12 | 58 | Inquiry |
| Auro Pharmaceuticals & Fine Chemicals Pvt. Ltd | 91-20-24475340 | Maharashtra, India | 19 | 58 | Inquiry |
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