N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE

CAS No.: 868359-05-1

Chemical Name:: N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE

Synonyms: WAY 213613;WAY 213613,WAY213613;N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE;L-Asparagine, N-[4-(2-bromo-4,5-difluorophenoxy)phenyl]-;N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine;(S)-2-amino-4-((4-(2-bromo-4,5-difluorophenoxy)phenyl)amino)-4-oxobutanoic acid

CBNumber:: CB32453432

Molecular Formula:: C16H13BrF2N2O4

Molecular Weight:: 415.19

MOL File:: 868359-05-1.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:06

Request For Quotation

N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Properties

Boiling point	565.6±50.0 °C(Predicted)
Density	1.664±0.06 g/cm3(Predicted)
storage temp.	Desiccate at RT
solubility	DMSO: >10mg/mL
form	white powder
pka	2.38±0.10(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501
Hazard Codes	Xn
Risk Statements	22
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Chemical Properties,Uses,Production

Uses

WAY 213613 is a selective non-substrate inhibitor of EAAT2. It is used in the methods of treating or inhibiting onset of Huntington''s disease with gene modulatory compounds.

Biological Activity

Potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC 50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards ionotropic and metabotropic glutamate receptors.

N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Suppliers

Global( 37)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	China	892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9268	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24647	58	Inquiry
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266	China	4362	55	Inquiry
https://hanhongsci.com/	021-54306202 18917919676	China	29977	58	Inquiry
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	China	9949	58	Inquiry
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	024-024-88590548 18341751992	China	891	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
RD International Technology Co., Limited	58
TargetMol Chemicals Inc.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
https://hanhongsci.com/	58
Shanghai Chaolan Chemical Technology Center	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58

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N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE WAY 213613 N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine L-Asparagine, N-[4-(2-bromo-4,5-difluorophenoxy)phenyl]- (S)-2-amino-4-((4-(2-bromo-4,5-difluorophenoxy)phenyl)amino)-4-oxobutanoic acid WAY 213613,WAY213613 868359-05-1 C16H13BrF2N2O4