tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate

tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate Structure
CAS No.
1147557-97-8
Chemical Name:
tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate
Synonyms
2-Boc-6-hydroxy-2-aza-spi...;2-Boc-6-hydroxy-2-aza-spiro[3.3]heptane;6-oxo-2-azaspiro[3.3]heptane-2-carboxylate;6-Hydroxy-2-azaspiro[3.3]heptane, N-BOC protected;tert-Butyl 2-hydroxy-6-azaspiro[3.3]heptane-6-carboxylate;tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate;1,1-Dimethylethyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate;6-Hydroxy-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester;tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate ISO 9001:2015 REACH;2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-hydroxy-, 1,1-diMethylethyl ester
CBNumber:
CB32470891
Molecular Formula:
C11H19NO3
Molecular Weight:
213.27
MOL File:
1147557-97-8.mol
Modify Date:
2023/4/27 16:27:43

tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate Properties

Melting point 127-129℃
Boiling point 316.6±42.0 °C(Predicted)
Density 1.17
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 14.84±0.20(Predicted)
form Solid
color White to Off-White
InChI InChI=1S/C11H19NO3/c1-10(2,3)15-9(14)12-6-11(7-12)4-8(13)5-11/h8,13H,4-7H2,1-3H3
InChIKey UMXXHZDEAZUQKZ-UHFFFAOYSA-N
SMILES C1C2(CC(O)C2)CN1C(OC(C)(C)C)=O

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2934999090

tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate Chemical Properties,Uses,Production

Uses

tert-?Butyl 6-?Hydroxy-?2-?azaspiro[3.3]?heptane-?2-?carboxylate is a reactant used in the synthesis of pharmaceuticals such as CNS penetrant CXCR2 antagonists for the potential treatment of CNS demyelinating.

tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate Preparation Products And Raw materials

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tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate 2-Boc-6-hydroxy-2-aza-spi... 2-Boc-6-hydroxy-2-aza-spiro[3.3]heptane 6-Hydroxy-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-hydroxy-, 1,1-diMethylethyl ester 6-Hydroxy-2-azaspiro[3.3]heptane, N-BOC protected tert-Butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate, 2-(tert-Butoxycarbonyl)-6-hydroxy-2-azaspiro[3.3]heptane tert-Butyl 2-hydroxy-6-azaspiro[3.3]heptane-6-carboxylate tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate ISO 9001:2015 REACH 1,1-Dimethylethyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate 1147557-97-8