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Trolox

Trolox  Structure
CAS No.
53188-07-1
Chemical Name:
Trolox
Synonyms
TROLOX;TROLOX;troloxc;TROLOX(R);trolox tm;TROLOXTM C;Trolox(R),97%;Trolox, 97% 1GR;Trolox, 97% 5GR;Trolox Standard
CBNumber:
CB7188583
Molecular Formula:
C14H18O4
Molecular Weight:
250.29
MOL File:
53188-07-1.mol
MSDS File:
SDS
Modify Date:
2024/5/9 14:47:05

Trolox Properties

Melting point 187-189 °C (lit.)
Boiling point 313.42°C (rough estimate)
Density 1.0616 (rough estimate)
refractive index 1.4970 (estimate)
storage temp. 2-8°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Also soluble in Water at alkalinepH.
form Crystalline Powder
pka 3.35±0.20(Predicted)
color White to faintly beige
BRN 1384051
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChIKey GLEVLJDDWXEYCO-UHFFFAOYSA-N
SMILES C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1
CAS DataBase Reference 53188-07-1(CAS DataBase Reference)
EPA Substance Registry System 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DJ2273000
HS Code  29339900
NFPA 704
0
2 0

Trolox price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 238813 (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% 53188-07-1 1G ₹8350 2022-06-14 Buy
Sigma-Aldrich(India) 238813 (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% 53188-07-1 5G ₹29043.48 2022-06-14 Buy
Sigma-Aldrich(India) 238813 (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% 53188-07-1 25G ₹51115.65 2022-06-14 Buy
TCI Chemicals (India) H0726 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid min. 98.0 % 53188-07-1 1G ₹7600 2022-05-26 Buy
TCI Chemicals (India) H0726 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid min. 98.0 % 53188-07-1 5G ₹10800 2022-05-26 Buy
Product number Packaging Price Buy
238813 1G ₹8350 Buy
238813 5G ₹29043.48 Buy
238813 25G ₹51115.65 Buy
H0726 1G ₹7600 Buy
H0726 5G ₹10800 Buy

Trolox Chemical Properties,Uses,Production

Chemical Properties

white to fainly beige crystalline powder

Definition

ChEBI: A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capa ity of complex mixtures.

Application

Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. lt is commonly used as a standard or positive control in antioxidant assays.  In addition, trolox is used to assessthe role of oxidative injury in processes like neuronal cell death and aging.  It is effective as adjunctivetherapy in the treatment of certain cancers.

General Description

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Mechanism of action

Trolox can protect against oxidative stress, genotoxicity and inflammation induced by CS through ROS scavenging mechanism, and serve as a potential antioxidant prevention strategy against oxidative injury of ATII cells in CS-related lung diseases.

Trolox Preparation Products And Raw materials

Global( 288)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
KVB Asta Life Sciences India Pvt. ltd. 91-0-9177003936 Hyderabad, India 59 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9624 58 Inquiry
TCI AMERICA 800-4238616 Americas 23662 75 Inquiry

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