Trolox
- CAS No.
- 53188-07-1
- Chemical Name:
- Trolox
- Synonyms
- TROLOX;TROLOX;troloxc;TROLOX(R);trolox tm;TROLOXTM C;Trolox(R),97%;Trolox, 97% 1GR;Trolox, 97% 5GR;Trolox Standard
- CBNumber:
- CB7188583
- Molecular Formula:
- C14H18O4
- Molecular Weight:
- 250.29
- MOL File:
- 53188-07-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/9 14:47:05
Melting point | 187-189 °C (lit.) |
---|---|
Boiling point | 313.42°C (rough estimate) |
Density | 1.0616 (rough estimate) |
refractive index | 1.4970 (estimate) |
storage temp. | 2-8°C |
solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Also soluble in Water at alkalinepH. |
form | Crystalline Powder |
pka | 3.35±0.20(Predicted) |
color | White to faintly beige |
BRN | 1384051 |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
InChI | InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17) |
InChIKey | GLEVLJDDWXEYCO-UHFFFAOYSA-N |
SMILES | C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1 |
CAS DataBase Reference | 53188-07-1(CAS DataBase Reference) |
EPA Substance Registry System | 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | DJ2273000 | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
Trolox price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 238813 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% | 53188-07-1 | 1G | ₹8350 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 238813 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% | 53188-07-1 | 5G | ₹29043.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 238813 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97% | 53188-07-1 | 25G | ₹51115.65 | 2022-06-14 | Buy |
TCI Chemicals (India) | H0726 | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid min. 98.0 % | 53188-07-1 | 1G | ₹7600 | 2022-05-26 | Buy |
TCI Chemicals (India) | H0726 | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid min. 98.0 % | 53188-07-1 | 5G | ₹10800 | 2022-05-26 | Buy |
Trolox Chemical Properties,Uses,Production
Chemical Properties
white to fainly beige crystalline powder
Definition
ChEBI: A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capa ity of complex mixtures.
Application
Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. lt is commonly used as a standard or positive control in antioxidant assays. In addition, trolox is used to assessthe role of oxidative injury in processes like neuronal cell death and aging. It is effective as adjunctivetherapy in the treatment of certain cancers.
General Description
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.
Mechanism of action
Trolox can protect against oxidative stress, genotoxicity and inflammation induced by CS through ROS scavenging mechanism, and serve as a potential antioxidant prevention strategy against oxidative injury of ATII cells in CS-related lung diseases.
Trolox Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
KVB Asta Life Sciences India Pvt. ltd. | 91-0-9177003936 | Hyderabad, India | 59 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9624 | 58 | Inquiry |
TCI AMERICA | 800-4238616 | Americas | 23662 | 75 | Inquiry |
Related articles
- Antioxidant effects and research of Trolox
- Trolox is a hydrophilic analogue of vitamin E. Trolox has been used as a standard antioxidant in antioxidant capacity assays.
- May 9,2024
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