Unii-na83F1sjsr

Unii-na83F1sjsr Structure
CAS No.
706782-28-7
Chemical Name:
Unii-na83F1sjsr
Synonyms
PiMavanserin Tartrate;Nuplazid;ACP-103;BVF-048;Unii-na83F1sjsr;ACP-103 tartrate;8-Octanedioic acid;Pimavanserin tartrare;Pimavanserin tartrate vv;Pimavanserin L-Hetartrate
CBNumber:
CB32494118
Molecular Formula:
C29H40FN3O8
Molecular Weight:
577.65
MOL File:
706782-28-7.mol
MSDS File:
SDS
Modify Date:
2024/11/17 16:00:36

Unii-na83F1sjsr Properties

storage temp. Store at -20°C
solubility DMSO:70.0(Max Conc. mg/mL);69.6(Max Conc. mM)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS05
Signal word  Danger
Hazard statements  H318-H317-H302+H332
Precautionary statements  P280-P305+P351+P338-P310-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
HS Code  29299090

Unii-na83F1sjsr Chemical Properties,Uses,Production

Description

Pimavanserin, developed by San Diego-based Acadia Pharmaceuticals, is a selective and potent serotonin 2A (5-HT2A) receptor inverse agonist. The USFDA approved this once-daily drug to treat the delusions and hallucinations associated with psychosis as a function of Parkinson’s disease. Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving as a selective inverse agonist of the serotonin 5-HT2A receptor while exhibiting 40-fold selectivity over the 5-HT2C receptor and having no significant affinity or activity with the 5-HT2B or dopamine receptors.

Uses

Pimavanserin tartrate is a 5-HT2A inverse agonist that reverses psychosis-like behaviours and has the potential to treat various other neuropsychiatric disorders such as schizophrenia and Parkinson’s disease.

Definition

ChEBI: A tartrate salt that is the hemitartrate salt of pimavanserin. An atypical antipsychotic that is used for treatment of hallucinations and delusions associated with Parkinson's disease.

Unii-na83F1sjsr Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 147)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry

Unii-na83F1sjsr Spectrum

N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide Unii-na83F1sjsr Pimavanserin tartrate or ACP 103 BVF-048 Pimavanserin tartrate,nuplazid N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea (2R,3R)-2,3-dihydroxybutanedioate (2:1) N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea (2R,3R)-2,3-dihydroxybutanedioate Urea,N-[(4-fluorobenzyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]-,(2R,3R)-2,3-dihydroxybutanediooate(2:1) ACP-103 tartrate 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea hemi((2R,3R)-2,3-dihydroxysuccinate) Pimavanserin tartrare 8-Octanedioic acid Pimavanserin Impurity reference Pimo van Serine L-tartrate Nuplazid ACP-103 PiMavanserin Tartrate Pimavanserin tartaric acid Pimavanserin tartrate vv Pimavanserin L-Hetartrate 706782-28-7 2C25H34FN3O2C4H6O6 C54H74F2N6O10