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8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Structure
CAS No.
298220-99-2
Chemical Name:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms
11-Fluoro Desloratadine;11-Fluoro Desloratadine HCl;Desloratadine EP Impurity A;11-Fluoro Dihydrodesloratadine;Desloratadine Impurity 1/Desloratadine EP Impurity A;Desloratadine EP Impurity A Desloratadine EP Impurity A;Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer);8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine;8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;8-chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
CBNumber:
CB32622191
Molecular Formula:
C19H20ClFN2
Molecular Weight:
330.83
MOL File:
298220-99-2.mol
Modify Date:
2024/4/12 23:00:59
Request For Quotation

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Properties

Melting point >192°C (dec.)
Boiling point 426.9±45.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.16±0.10(Predicted)
form Solid
color Off-White to Pale Orange

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Chemical Properties,Uses,Production

Uses

11-Fluoro Desloratadine is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Suppliers

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Chemicea Pharmaceuticals Pvt Ltd 58
Hubei Ipure Biology Co., Ltd 58
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298220-99-2(8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine)Related Search:

Desloratadine Epoxide DESLORATADINE-D4 Desloratadine D5 Desloratadine N-Hydroxypiperidine Desloratadine IMpurity B
Desloratadine IMpurity 3 Desloratadine IMpurity 1 Desloratadine IMpurity 6 8-Dechloro-9-chloro Desloratadine Desloratadine Impurity
Desloratadine Desloratadine Pyridine N-oxide Desloratadine Citric Amide Iso Desloratadine 5,6-Dehydro-N-methyl Desloratadine
IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate 8-Deschloro-8-bromo-N-methyl Desloratadine Desloratadine N-Carboxylic Acid Methyl Ester
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11-Fluoro Desloratadine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Desloratadine EP Impurity A 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b]pyridin-11-yl]piperidine 8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine Desloratadine Impurity 1/Desloratadine EP Impurity A 11-Fluoro Desloratadine HCl 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)- 8-chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 11-Fluoro Dihydrodesloratadine Desloratadine Impurity 1 (Desloratadine EP Impurity A Monomer) 8-Chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (Desloratadine Impurity) Desloratadine EP Impurity A Desloratadine EP Impurity A 298220-99-2 C19H20N2ClF C19H20ClFN2 Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals