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GUANABENZ

GUANABENZ Structure
CAS No.
5051-62-7
Chemical Name:
GUANABENZ
Synonyms
Rexitene;nsc-68982;GUANABENZ;Callosum benzyl;GUANABENZ USP/EP/BP;Guanabenz (WY 8678);1-(2,6-DICHLOROBENZYLIDENEAMINO)GUANIDINE;n-(2,6-dichlorobenzylidene)amino]guanidine;n-(2,6-dichlorobenzylidene)-n’-amidinohydrazine;2-(2,6-Dichlorobenzylidene)hydrazine-1-carboximidamide
CBNumber:
CB3263851
Molecular Formula:
C8H8Cl2N4
Molecular Weight:
231.08
MOL File:
5051-62-7.mol
Modify Date:
2023/9/20 16:43:00

GUANABENZ Properties

Melting point 227-229° (dec)
Boiling point 353.9±52.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 12 mg/mL (51.93 mM);Ethanol: 15 mg/mL (64.91 mM)
pka pKa 8.1 (Uncertain)
Water Solubility Water: Insoluble

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS07
Signal word  Warning
Hazard statements  H302-H361-H332-H312
Precautionary statements  P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P201-P202-P281-P308+P313-P405-P501
Hazard Codes  Xn
Risk Statements  20/21/22-62
Safety Statements  22-36/37/39
RIDADR  3249
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III

GUANABENZ Chemical Properties,Uses,Production

Description

Guanabenz is an α2-adrenergic agonist that exhibits pronounced hypotensive action, and that is associated with a reduction of overall peripheral vascular resistance, decline in frequency of cardiac contractions, and reduced cardiac output.

Uses

alpha agonists

Purification Methods

Crystallise the guanidine from MeCN and store it in a CO2–free atmosphere. The monoHCl [23256-5-0] has m 178o(dec) [solubility w% at 25o is 1.1(H2O), 5(EtOH), 0.1(EtOAc), 0.06(CHCl3)]. It is an antihypertensive drug. [Holmes et al. Drugs 26 212 1983.]

GUANABENZ Preparation Products And Raw materials

Raw materials

Preparation Products

GUANABENZ Suppliers

Global( 51)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9640 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 50000 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry

GUANABENZ Spectrum

GUANABENZ 2-[(2,6-dichlorophenyl)methylene]-hydrazinecarboximidamide n-(2,6-dichlorobenzylidene)amino]guanidine n-(2,6-dichlorobenzylidene)-n’-amidinohydrazine nsc-68982 Rexitene HydrazinecarboxiMidaMide, 2-[(2,6-dichlorophenyl)Methylene]- 1-(2,6-DICHLOROBENZYLIDENEAMINO)GUANIDINE GUANABENZ USP/EP/BP Guanabenz (WY 8678) 2-(2,6-Dichlorobenzylidene)hydrazine-1-carboximidamide Callosum benzyl GUANABENZ,inhibit,Adrenergic Receptor,high blood pressure,Beta Receptor,antiparasitic,Inhibitor,antihypertensive,Parasite 5051-62-7 C8H8Cl2N4 Analytical Standards Analytical Chromatography Product Catalog Alphabetic