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AMT HYDROCHLORIDE

AMT HYDROCHLORIDE Structure
CAS No.
21463-31-0
Chemical Name:
AMT HYDROCHLORIDE
Synonyms
4H-1;AMT HCL;AMT HYDROCHLORIDE;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE;4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1)
CBNumber:
CB3266443
Molecular Formula:
C5H10N2S.ClH
Molecular Weight:
166.67
MOL File:
21463-31-0.mol
Modify Date:
2023/6/30 15:45:59
Request For Quotation

AMT HYDROCHLORIDE Properties

Melting point 146-150°C
storage temp. 0-6°C
solubility DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml
form A crystalline solid
Water Solubility Soluble to 10 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335
Precautionary statements  P261-P264-P271-P280-P304+P340-P305+P351+P338-P312-P337+P313-P403+P233-P405-P501
HS Code  29309099
NFPA 704
0
2 0

AMT HYDROCHLORIDE Chemical Properties,Uses,Production

Description

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.

Chemical Properties

white to off-white powder

Biological Activity

Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

AMT HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

AMT HYDROCHLORIDE Suppliers

Global( 43)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 China 9552 58 Inquiry
Shanghai Tachizaki Biomedical Research Center 18014399201 China 2542 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8736 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4659 58 Inquiry
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4309 55 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Suzhou Rovathin Foreign Trade Co.,Ltd 58
Shanghai Tachizaki Biomedical Research Center 58
Cayman Chemical Company 81
Shanghai Yifei Biotechnology Co. , Ltd. 58
BOC Sciences 65
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Lollane Biological Technology Co.,Ltd. 55

21463-31-0(AMT HYDROCHLORIDE)Related Search:

AMT HYDROCHLORIDE
5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE AMT HYDROCHLORIDE AMT HCL 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL 4H-1 4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1) 21463-31-0 C5H11ClN2S C5H10N2SHCl Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Biochemicals and Reagents BioChemical L to O Nitric Oxide Synthase (iNOS)