ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione Structure
CAS No.
93269-35-3
Chemical Name:
(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione
Synonyms
Methylprednisolone EP IMP G;Methylprednisolone EP Impurity G;17,21-dihydroxy-6α-methylpregna-1,4,9(11)-triene-3,20-dione;Methylprednisolone Impurity 7(Methylprednisolone EP Impurity G);(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione;"(6a)-17,21-Dihydroxy-6-methylpregna-1,4,9(11)-triene-3,20-dione";(6alpha)-17,21-Dihydroxy-6-methylpregna-1,4,9(11)-triene-3,20-dione;Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-6-methyl-, (6α)-;(6S,8S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
CBNumber:
CB32694570
Molecular Formula:
C22H28O4
Molecular Weight:
356.46
MOL File:
93269-35-3.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:44:01

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione Properties

Boiling point 548.3±50.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.51±0.70(Predicted)
color White to Pale Yellow

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione Chemical Properties,Uses,Production

Uses

(6α)-17,21-Dihydroxy-6-methylpregna-1,4,9(11)-triene-3,20-dione, is a metabolite of Prednisolone (P703740), which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. It is also the active metabolite of the drug prednisone.

(6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylprednisolone EP Impurity G Methylprednisolone Impurity 7(Methylprednisolone EP Impurity G) Methylprednisolone EP IMP G Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-6-methyl-, (6α)- 17,21-dihydroxy-6α-methylpregna-1,4,9(11)-triene-3,20-dione (6S,8S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one "(6a)-17,21-Dihydroxy-6-methylpregna-1,4,9(11)-triene-3,20-dione" (6alpha)-17,21-Dihydroxy-6-methylpregna-1,4,9(11)-triene-3,20-dione (6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione 93269-35-3 Pharmaceuticals, Intermediates & Fine Chemicals, Steroids