EveroliMus-d4
- CAS No.
- 1338452-54-2
- Chemical Name:
- EveroliMus-d4
- Synonyms
- Everolimus-d4;EveroliMus-d4 (~90%);EVEROLIMUS (2-HYDROXYETHYL-D4, 98%);Everolimus-d4 (Everolimus Impurity);Everolimus Impurity 24(Everolimus-d4);Everolimus D4Q: What is Everolimus D4 Q: What is the CAS Number of Everolimus D4 Q: What is the storage condition of Everolimus D4 Q: What are the applications of Everolimus D4
- CBNumber:
- CB32714520
- Molecular Formula:
- C53H79D4NO14
- Molecular Weight:
- 962.249067112
- MOL File:
- 1338452-54-2.mol
- Modify Date:
- 2024/7/2 8:55:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H372 |
| Precautionary statements | P260-P264-P270-P314-P501 |
EveroliMus-d4 price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E-070 | Everolimus-D4 solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1338452-54-2 | 1ML | ₹56051.85 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| E-070 | 1ML | ₹56051.85 | Buy |
EveroliMus-d4 Chemical Properties,Uses,Production
Description
Everolimus-d4 is intended for use as an internal standard for the quantification of everolimus by GC- or LC-MS. Everolimus is a hydroxyethyl ether form of rapamycin that inhibits mTOR signaling through both mTORC1 and mTORC2 when added to cells at 20 nM. It is orally available and shows improved pharmacokinetics and pharmacodynamics over rapamycin. Through its inhibition of mTOR, everolimus inhibits cell proliferation, metabolism, and angiogenesis in certain types of cancer. It also acts as an immunosuppressive agent in the context of organ transplantation.
General Description
A stable-labeled internal standard for the immunosuppressant Everolimus, marketed as Zortress? and Certican for use in organ transplantation and Afinitor? for treatment of kidney and pancreatic cancers. Clinical laboratories quantitate everolimus levels in patient whole blood samples using LC-MS/MS. While many everolimus LC-MS/MS methods use 32-desmethoxyrapamycin or ascomycin as an internal standard, higher levels of variability / lower levels of reproducibility may occur in the analysis along with the potential for interferences. Use of a stable-labeled analog of everolimus is the best choice to minimize variability or mitigate any potential interference in LC-MS/MS analysis.
EveroliMus-d4 Preparation Products And Raw materials
Raw materials
Preparation Products
EveroliMus-d4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25014 | 65 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | China | 6210 | 58 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12584 | 58 | Inquiry |
| PureChemland Co.,Ltd. | 19150123681 | China | 3242 | 58 | Inquiry |
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