DBCO-amine
![DBCO-amine Structure](CAS/20150408/GIF/1255942-06-3.gif)
- CAS No.
- 1255942-06-3
- Chemical Name:
- DBCO-amine
- Synonyms
- DBCO-NH2;DBCO-amine;DBCO-CH2CH2NH2;DBCO-(CH2)2-NH2;ADIBO-CH2CH2NH2·TFA;DBCO-(CH2)3-NH2.TFA;DBCO-(CH2)2-NH2.TFA;Dibenzocyclooctyne-amine;DBCO-Amine (DBCO amine);Azadibenzocylooctyne-amine
- CBNumber:
- CB32730210
- Molecular Formula:
- C18H16N2O
- Molecular Weight:
- 276.33
- MOL File:
- 1255942-06-3.mol
- Modify Date:
- 2024/3/28 13:39:29
Melting point | 86-96°C |
---|---|
Boiling point | 549.9±50.0 °C(Predicted) |
Density | 1.25±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
pka | 8.81±0.10(Predicted) |
form | Solid |
color | Yellow to Orange |
InChI | InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2 |
InChIKey | PQFQVUMDOWUGMK-CHMOPDDRSA-N |
SMILES | C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCN |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
WGK Germany | 3 |
HS Code | 29339900 |
DBCO-amine price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 761540 | Dibenzocyclooctyne-amine for Copper-free Click Chemistry | 1255942-06-3 | 10MG | ₹3842.88 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 761540 | Dibenzocyclooctyne-amine for Copper-free Click Chemistry | 1255942-06-3 | 100MG | ₹27495.5 | 2022-06-14 | Buy |
DBCO-amine Chemical Properties,Uses,Production
Uses
Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
Properties and Applications
DBCO-amine is an aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition (SPAAC, also known as “copper-free click chemistry”). The DBCO moiety reacts selectively with azides via SPAAC to form stable triazole linkages. The amine terminus of the molecule reacts with carboxylic acids and their active esters to form stable amide bonds. Insoluble in water, DBCO-amine is slightly soluble to sparingly soluble in most organic solvents. It recommends dimethylsulfoxide (DMSO), N, N’-dimethylformamide (DMF), or N, N’-dimethylacetamide (DMAC) as solvents for this product. DBCO-amine is relatively insensitive to bases and can be used in the presence of aqueous bases. This product is acid-sensitive. It should not be subjected to pH <5 during reaction or workup. The product should always be stored at -20°C when not in use.
DBCO-amine Preparation Products And Raw materials
DBCO-amine Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Grr Fine Chem/Grr Exports | 91-79-40031771 | Gujarat, India | 405 | 58 | Inquiry |
HUBEI DING KOSIN TECHNOLOGY | +8613524650931 | China | 953 | 58 | Inquiry |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | China | 2996 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7287 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |