DIBENZAZEPINE
- CAS No.
- 209984-56-5
- Chemical Name:
- DIBENZAZEPINE
- Synonyms
- GSI-XX;CS-366;YO01027;DIBENZAZEPINE;Deshydroxy LY-411575;6-Chloro-α-Tetralone;YO-01027 (Dibenzazepine);γ-Secretase Inhibitor XX;Dibenzazepine (YO-01027);γ-Secretase Inhibitor XX
- CBNumber:
- CB11234300
- Molecular Formula:
- C26H23F2N3O3
- Molecular Weight:
- 463.48
- MOL File:
- 209984-56-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H335-H315-H319 | |||||||||
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29337900 | |||||||||
NFPA 704 |
|
DIBENZAZEPINE price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0649 | Deshydroxy LY-411575 ≥98% (HPLC) | 209984-56-5 | 5MG | ₹11506.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0649 | Deshydroxy LY-411575 ≥98% (HPLC) | 209984-56-5 | 25MG | ₹46374.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 565789 | γ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ~72% in Tg257 | 209984-56-5 | 500μG | ₹29850 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 565789 | γ-Secretase Inhibitor XX - CAS 209984-56-5 - Calbiochem This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ~72% in Tg257 | 209984-56-5 | 1MG | ₹37040 | 2022-06-14 | Buy |
DIBENZAZEPINE Chemical Properties,Uses,Production
Description
γ-
Chemical Properties
White Solid
Uses
DIBENZAZEPINE is a dipeptidic-secretase inhibitor and a antiAlzheimer agent.
General Description
A cell-permeable, potent γ-secretase inhibitor that significantly lowers both brain and plasma Aβ40 levels by ~72% in Tg2576 mutant APP transgenic mouse model (100 μmol/kg, b.i.d). Induces a heterogeneous reorganization of the crypt structural-proliferative units in the intestinal tract and of the stem cell niche in the colon. Also potently inhibits Notch processing (IC50 = 1.7 nM in SupT1 cells) and induces conversion of proliferative crypt cells to post-mitotic goblet cells in both the C57BL/6 and ApcMin mouse models (10 μmol/kg, i.p).
DIBENZAZEPINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32835 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29821 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
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