BETA-SECRETASE INHIBITOR IV

BETA-SECRETASE INHIBITOR IV Structure
CAS No.
797035-11-1
Chemical Name:
BETA-SECRETASE INHIBITOR IV
Synonyms
BACE-1 inhibitor;β-Secretase Inhibitor IV;γ-Secretase Inhibitor IV;β-Secretase Inhibitor IV;BETA-SECRETASE INHIBITOR IV;βSecretase Inhibitor IV,β Secretase Inhibitor IV;N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE;N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide;3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide;1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
CBNumber:
CB8835547
Molecular Formula:
C31H38N4O5S
Molecular Weight:
578.72
MOL File:
797035-11-1.mol
Modify Date:
2024/7/2 8:55:38

BETA-SECRETASE INHIBITOR IV Properties

Density 1.30±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka 13.72±0.46(Predicted)
color Off-white to light yellow

BETA-SECRETASE INHIBITOR IV Chemical Properties,Uses,Production

Uses

beta-Secretase Inhibitor IV is a compound that binds to the active site of BACE-1 and potently blocks its proteolytic activity.

BETA-SECRETASE INHIBITOR IV Preparation Products And Raw materials

Raw materials

Preparation Products

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BETA-SECRETASE INHIBITOR IV 1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]- N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide β-Secretase Inhibitor IV N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE BACE-1 inhibitor β-Secretase Inhibitor IV 3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide γ-Secretase Inhibitor IV βSecretase Inhibitor IV,β Secretase Inhibitor IV 797035-11-1 C31H38N4O5S Human β-secretase (BACE-1) inhibitor.