ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >Gamma-secretase inhibitors >RO4929097

RO4929097

RO4929097 Structure
CAS No.
847925-91-1
Chemical Name:
RO4929097
Synonyms
CS-14;R4733;RG-4733;Ro492097;RO4929097;RO04929097);RO4929097, >=98%;RO4929097 (RG-4733);RO-4929097;RO 4929097;RO4929097;RO-4929097;RO 4929097
CBNumber:
CB12512519
Molecular Formula:
C22H20F5N3O3
Molecular Weight:
469.4
MOL File:
847925-91-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:00

RO4929097 Properties

Boiling point 696.3±55.0 °C(Predicted)
Density 1.40
storage temp. Store at -20°C
solubility ≥23.47 mg/mL in DMSO; insoluble in H2O; ≥45.2 mg/mL in EtOH with ultrasonic
form solid
pka 12.35±0.46(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
HS Code  29242990
NFPA 704
0
2 0

RO4929097 Chemical Properties,Uses,Production

Uses

Ro 4929097 acts as a γ-secretase inhibitor used in the treatment of those suffering from solid tumors. It is used to treat pancreatic adenocarcinoma.

Definition

ChEBI: A member of the class of dibenzoazepines that is the amide formed from formal condensation of the carboxy group of 2,2-dimethyl-3-oxo-3-[(2,2,3,3,3-pentafluoropropyl)amino]propanoic acid with the amino group of (7S)-7-amino-5,7-dihydrodibe zo[b,d]azepin-6-one.

RO4929097 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 113)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry

RO4929097 Spectrum

RO4929097 N1-[(7S)-6,7-Dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)propanediamide Propanediamide, N1-[(7S)-6,7-dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)- N1-[(7S)-6,7-Dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)propanediamide Ro 4929097 N1-[(7S)-6,7-Dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropr Ro 4929097 N1-[(7S)-6,7-Dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)propanediamide RO4929097, >=98% CS-14 RO4929097;RO-4929097;RO 4929097 Ro492097 RO4929097 (RG-4733) RO-4929097;RO 4929097 RO 4929097, 98%, a γ secretase inhibitor RG-4733 R4733 RO04929097) (S)-2,2-Dimethyl-N1-(6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N3-(2,2,3,3,3-pentafluoropropyl)malonamide RO4929097 γ-Secretase inhibitor RO-4929097 847925-91-1 47925-91-1 C22H20F5N3O3 Inhibitors API