Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >Gamma-secretase inhibitors >Avagacestat (BMS-708163)

Avagacestat (BMS-708163)

Avagacestat (BMS-708163) Structure
CAS No.
1146699-66-2
Chemical Name:
Avagacestat (BMS-708163)
Synonyms
CS-262;BMS-708163;Avagacestat;BMS-708163, >=98%;BMS708163;BMS 708163;BMS-708163 (Avagacestat);Avagacestat (BMS-708163);BMS708163;BMS 708163;AVAGACESTAT;Avagacestat BMS-708163 BMS708163;(R)-2-(4-Chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-phenylsulfonamido)-5,5,5-trifluoro
CBNumber:
CB32470907
Molecular Formula:
C20H17ClF4N4O4S
Molecular Weight:
520.89
MOL File:
1146699-66-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:06
Request For Quotation

Avagacestat (BMS-708163) Properties

Density 1.488
storage temp. Store at -20°C
solubility insoluble in H2O; ≥177.6 mg/mL in DMSO; ≥47.6 mg/mL in EtOH with ultrasonic
form Powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

Avagacestat (BMS-708163) Chemical Properties,Uses,Production

Uses

Avagacestat acts as a γ-secretase inhibitor allowing for treatment of ALzheimer’s disease. On addition it has seen uses targeting embryonic signaling pathways, which control stem cell and cellular development process in cancer therapy.

Avagacestat (BMS-708163) Preparation Products And Raw materials

Raw materials

PentanaMide, 2-[[(4-chlorophenyl)sulfonyl]aMino]-5,5,5-trifluoro-, (2R)- 1,2,4-Oxadiazole, 3-[4-(broMoMethyl)-3-fluorophenyl]- Triethyl orthoformate 4-Chlorobenzenesulfonyl chloride

Preparation Products

Avagacestat (BMS-708163) Suppliers

Global( 109)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7621 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Jinan Carbotang Biotech Co.,Ltd. 58
BOC Sciences 58
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
LEAP CHEM CO., LTD. 58
TargetMol Chemicals Inc. 58

Avagacestat (BMS-708163) Spectrum

Avagacestat (BMS-708163)(1146699-66-2)1HNMR

1146699-66-2(Avagacestat (BMS-708163))Related Search:

STAT1 3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol CCT 137690 Tariquidar (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione Torin 1 Telaprevir CUDC-101 Brivanib alaninate
AC480 (BMS-599626) Semagacestat ABT 737 DAPT RO4929097
LY2811376 MK-0752 Pentanamide
chevron_left

1of4

chevron_right
(2R)-2-[N-[(4-Chlorophenyl)sulfonyl]-N-[2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl]amino]-5,5,5-trifluoropentanamide BMS-708163 (R)-2-(4-chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)phenylsulfonamido)-5,5,5-trifluoropentanamide BMS-708163 (Avagacestat) Avagacestat Avagacestat (BMS-708163) (R)-2-(4-Chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-phenylsulfonamido)-5,5,5-trifluoropen (2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide (2R)-2-[N-[(4-Chlorophenyl)sulfonyl]-N-[2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl]amino]-5,5,5-trifluoropentanamide BMS-708163 BMS-708163, >=98% (2R)-2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-pentanamide (R)-2-(4-Chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-phenylsulfonamido)-5,5,5-trifluoro BMS708163;BMS 708163 CS-262 BMS708163;BMS 708163;AVAGACESTAT Pentanamide, 2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-, (2R)- Avagacestat BMS-708163 BMS708163 (2R)-[(4-Chloro-benzenesulfonyl)-(2-fluoro-4-[1,2,4]oxadiazol-3-yl-benzyl)-amino]-5,5,5-trifluoro-pentanoic acid amide 1146699-66-2 C20H17ClF4N4O4S Inhibitors