ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >Proteasome inhibitors >(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
![(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Structure](CAS/GIF/1072833-77-2.gif)
- CAS No.
- 1072833-77-2
- Chemical Name:
- (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
- Synonyms
- IxazoMib;MLN2238;Ixazomib-d7;CS-1976;MLN2238(Ixazomib);MLN2238(iaxzomib);ixazomib(MLN2238);Ixazomib (MLN-9708);Ixazomib (10mM in DMSO);MLN2238;MLN 2238;MLN-2238
- CBNumber:
- CB62521080
- Molecular Formula:
- C14H19BCl2N2O4
- Molecular Weight:
- 361.03
- MOL File:
- 1072833-77-2.mol
- Modify Date:
- 2024/3/28 13:39:29
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H362-H360 |
Precautionary statements | P201-P260-P263-P264-P270-P308+P313 |
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Chemical Properties,Uses,Production
Uses
Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.
Definition
ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixa omib citrate, it is used in combination therapy for treatment of multiple myeloma.
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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1072833-77-2((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid)Related Search:
Ixazomib citrate (USAN)
Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-
Ixazomib Impurity 1
CUDC-101
Brivanib alaninate
AC480 (BMS-599626)
1H-indazole-7-carboxylic acid
tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate
Niraparib
(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
ixazomib(MLN2238)
B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238)
MLN2238(iaxzomib)
MLN2238(Ixazomib)
MLN2238;MLN 2238;MLN-2238
IXAZOMIB;MLN 2238;MLN-2238
CS-1976
1-(2-(2,5-dichlorobenzamido)acetamido)-
3-methylbutylboronic acid
Ixazomib (MLN-9708)
Ixazomib, 98%, a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM)
(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid
Boronic acid, B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-
(R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbuyl)boronic acid
Ixazomib (10mM in DMSO)
Ixazomib-13C2,15NQ: What is
Ixazomib-13C2,15N Q: What is the CAS Number of
Ixazomib-13C2,15N
MLN2238
IxazoMib
Ixazomib-d7
1072833-77-2
C14H19BCl2N2O4
Inhibitors
Inhibitor
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