ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >CUDC-101
CUDC-101
![CUDC-101 Structure](CAS/GIF/1012054-59-9.gif)
- CAS No.
- 1012054-59-9
- Chemical Name:
- CUDC-101
- Synonyms
- CURIS;CS-330;CUDC101;CUDC-101;CUDC-101, >=98%;CUDC101;CUDC 101;CUDC101; CUDC 101; CUDC-101.;7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide;7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide
- CBNumber:
- CB12500941
- Molecular Formula:
- C24H26N4O4
- Molecular Weight:
- 434.49
- MOL File:
- 1012054-59-9.mol
- Modify Date:
- 2023/5/18 11:31:22
Melting point | 174-177℃ |
---|---|
Density | 1.28 |
storage temp. | -20°C |
solubility | DMSO: soluble |
pka | 9.47±0.20(Predicted) |
form | solid |
color | White or off-white |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
InChIKey | PLIVFNIUGLLCEK-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P280-P305+P351+P338 |
WGK Germany | 3 |
CUDC-101 price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | EPS003 | CUDC 101 A potent inhibitor of HDACs and receptor tyrosine kinases | 1012054-59-9 | 5MG | ₹19095.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | EPS003 | CUDC 101 A potent inhibitor of HDACs and receptor tyrosine kinases | 1012054-59-9 | 25MG | ₹71445 | 2022-06-14 | Buy |
CUDC-101 Chemical Properties,Uses,Production
Uses
CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer.
General Description
A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively.
Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
CUDC-101 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 131)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
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CUDC101
CUDC-101
7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide
HeptanaMide, 7-[[4-[(3-ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxy-
7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide
7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide CUDC-101
7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide
CUDC-101, >=98%
CUDC101; CUDC 101; CUDC-101.
CS-330
CUDC101;CUDC 101
CURIS
1012054-59-9
Inhibitor
Antineoplastic
Inhibitors