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CUDC-101

CAS No.: 1012054-59-9

Chemical Name:: CUDC-101

Synonyms: CURIS;CS-330;CUDC101;CUDC-101;CUDC-101, >=98%;CUDC101;CUDC 101;CUDC101; CUDC 101; CUDC-101.;7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide;7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide

CBNumber:: CB12500941

Molecular Formula:: C24H26N4O4

Molecular Weight:: 434.49

MOL File:: 1012054-59-9.mol

Modify Date:: 2023/5/18 11:31:22

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CUDC-101 Properties

Melting point	174-177℃
Density	1.28
storage temp.	-20°C
solubility	DMSO: soluble
pka	9.47±0.20(Predicted)
form	solid
color	White or off-white
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey	PLIVFNIUGLLCEK-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P280-P305+P351+P338
WGK Germany	3

CUDC-101 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	EPS003	CUDC 101 A potent inhibitor of HDACs and receptor tyrosine kinases	1012054-59-9	5MG	₹19095.3	2022-06-14	Buy
Sigma-Aldrich(India)	EPS003	CUDC 101 A potent inhibitor of HDACs and receptor tyrosine kinases	1012054-59-9	25MG	₹71445	2022-06-14	Buy

Product number	Packaging	Price	Buy
EPS003	5MG	₹19095.3	Buy
EPS003	25MG	₹71445	Buy

CUDC-101 Chemical Properties,Uses,Production

Uses

CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer.

General Description

A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively.

Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.

CUDC-101 Preparation Products And Raw materials

Raw materials

Preparation Products

CUDC-101 Suppliers

Global( 131)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49392	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58

CUDC-101 Spectrum

CUDC-101(1012054-59-9)MS

1012054-59-9(CUDC-101)Related Search:

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5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione Torin 1 Telaprevir Avagacestat (BMS-708163) RO4929097

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JNJ-26481585 Mocetinostat (MGCD0103) Entinostat

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CUDC101 CUDC-101 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide HeptanaMide, 7-[[4-[(3-ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxy- 7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide CUDC-101 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide CUDC-101, >=98% CUDC101; CUDC 101; CUDC-101. CS-330 CUDC101;CUDC 101 CURIS 1012054-59-9 Inhibitor Antineoplastic Inhibitors