Sodium 2-propylpentanoate
- CAS No.
- 1069-66-5
- Chemical Name:
- Sodium 2-propylpentanoate
- Synonyms
- SODIUM VALPROATE;VALPROATE SODIUM;VALPROIC ACID SODIUM SALT;valerin;Depacon;VALDISOVAL;2-propylpentanoate;Valproic acid sodiuM salt (SodiuM valproate);proate;kw6066n
- CBNumber:
- CB5666438
- Molecular Formula:
- C8H15NaO2
- Molecular Weight:
- 166.19
- MOL File:
- 1069-66-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/29 16:45:47
| Melting point | 300 °C |
|---|---|
| Density | 1.0803 g/cm3 |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | Fine Powder |
| pka | 4.8(at 25℃) |
| color | White |
| PH | 6.0～9.0 (50g/l, 25℃) |
| Water Solubility | soluble |
| Merck | 14,9913 |
| BCS Class | 1 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months |
| InChIKey | AEQFSUDEHCCHBT-UHFFFAOYSA-M |
| CAS DataBase Reference | 1069-66-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H361d | |||||||||
| Precautionary statements | P201-P202-P264-P270-P301+P312-P308+P313 | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 22-61-36/38-36/37/38 | |||||||||
| Safety Statements | 36/37-53-45-37/39-26-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YV7876000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| Toxicity | LD50 orally in mice: 1700 mg/kg (Meunier) | |||||||||
| NFPA 704 |
|
Sodium 2-propylpentanoate price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P4543 | Valproic acid sodium salt 98% | 1069-66-5 | 10G | ₹4990.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P4543 | Valproic acid sodium salt 98% | 1069-66-5 | 25G | ₹9212.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P4543 | Valproic acid sodium salt 98% | 1069-66-5 | 100G | ₹24984.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 676380 | Valproic Acid, Sodium Salt - CAS 1069-66-5 - Calbiochem A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC?? = 400 μM for HDAC1). | 1069-66-5 | 5G | ₹8310 | 2022-06-14 | Buy |
| TCI Chemicals (India) | S0894 | Sodium Valproate | 1069-66-5 | 25G | ₹5000 | 2022-05-26 | Buy |
Sodium 2-propylpentanoate Chemical Properties,Uses,Production
Chemical Properties
White Solid. Colorless crystalline powder, hygroscopic, very soluble in water (ca. 0.66 g/mL of solution), soluble in ethanol (ca. 0.2 g/mL of solution), practically insoluble in chloroform and diethyl ether.
Uses
Antiepileptic; increases levels of GABA in the brain
Definition
ChEBI: The sodium salt of valproic acid.
brand name
Convulex (Byk – Gulden, Promonta Lundbeck), Depakene/Depakote/ Valcote (Abbott), Depakine/Epilim/Ergenyl (Sanofi), Leptilan (Novartis), Orfiril (Desitin Arzneimittel)
General Description
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase activity (IC50 = 400 μM for HDAC1). Induces differentiation and inhibits proliferation of cell lines derived from human malignant gliomas. At therapeutic levels (350 μM-1.04 mM), causes inositol depletion, inhibits both GSK-3α and -3β, activates the ERK pathway, and produces neurotropic effects. Has been used as an anti-epileptic agent. Also reported to stimulate peroxisome proliferator-activated receptor (PPAR) activity. Displays a potent teratogenic activity in humans and rodent models.
Biological Activity
Histone deacetylase inhibitor (IC 50 = 400 μ M) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases A β production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na + channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2.
Sodium 2-propylpentanoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Element Chemilink Pvt. Ltd. | +91-6358814008 +91-6358814008 | Gujarat, India | 31 | 58 | Inquiry |
| AARTIA KEM SCIENCE | +91-8291072530 +91-8291072530 | Maharashtra, India | 70 | 58 | Inquiry |
| Cefa-Cilinas Biotics Pvt Ltd | +91-7875033155 +91-8080701561 | Maharashtra, India | 121 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| Sekhment pharmaventures | +91-9030088669 +91-9030088669 | Mumbai, India | 105 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| Roaq Chemicals Pvt Ltd | +91-9227103654 +91-9227103654 | Gujarat, India | 5 | 58 | Inquiry |
| Mascot Industries Pvt., Ltd. | +91-9825849755 +91-9825849755 | Ahmedabad, India | 16 | 58 | Inquiry |
| Chempifine Chemicals | +91-2225667766 +91-2225667766 | Punjab, India | 144 | 58 | Inquiry |
| Ishita Active Pharma Ingredients Pvt. Ltd | +91-7927910233 +91-7927910233 | Ahmedabad, India | 3 | 58 | Inquiry |