Sodium citrate
- CAS No.
- 68-04-2
- Chemical Name:
- Sodium citrate
- Synonyms
- TRI-SODIUM CITRATE;BUFFER SOLUTION;CITRIC ACID TRISODIUM SALT;ANHYDROUS SODIUM CITRATE;citrate concentrated solution;Citric acid sodium;SODIUM CITRATE TRIBASIC;CITRIC ACID TRISODIUM SALT, ANHYDROU;citreme;abs9132
- CBNumber:
- CB7360958
- Molecular Formula:
- C6H9NaO7
- Molecular Weight:
- 216.12
- MOL File:
- 68-04-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/23 11:40:06
| Melting point | 300°C |
|---|---|
| Density | 1.008 g/mL at 20 °C |
| FEMA | 3026 | SODIUM CITRATE |
| storage temp. | 2-8°C |
| solubility | Water (Slightly) |
| form | Liquid |
| color | White to off-white |
| PH | 8.59(1 mM solution);8.9(10 mM solution);9.04(100 mM solution);9.26(1000 mM solution) |
| Odor | at 100.00?%. odorless |
| Water Solubility | Soluble in water. |
| Sensitive | Hygroscopic |
| λmax | λ: 260 nm Amax: ≤0.1 |
| Stability | Hygroscopic |
| InChIKey | HRXKRNGNAMMEHJ-UHFFFAOYSA-K |
| LogP | -0.280 (est) |
| CAS DataBase Reference | 68-04-2(CAS DataBase Reference) |
| EPA Substance Registry System | Trisodium citrate (68-04-2) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi,C | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Risk Statements | 22-40-48/20/22-41-37/38-36-35 | |||||||||
| Safety Statements | 36-24/25-39-26-45-36/37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GE8300000 | |||||||||
| F | 34 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29181500 | |||||||||
| Toxicity | LD50 in rats, mice (mmol/kg): 6.0, 5.5 i.p. (Gruber, Halbeisen) | |||||||||
| NFPA 704 |
|
Sodium citrate price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S5770 | Citrate Concentrated Solution BioReagent, suitable for coagulation assays, 4?% (w/v) | 68-04-2 | 50ML | ₹2522.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3674 | Citric acid trisodium salt anhydrous, ≥98% (GC) | 68-04-2 | 100G | ₹3290.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5770 | Citrate Concentrated Solution BioReagent, suitable for coagulation assays, 4?% (w/v) | 68-04-2 | 10X50ML | ₹16334.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3674 | Citric acid trisodium salt anhydrous, ≥98% (GC) | 68-04-2 | 500G | ₹4450 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3674 | Citric acid trisodium salt anhydrous, ≥98% (GC) | 68-04-2 | 1KG | ₹5780.55 | 2022-06-14 | Buy |
Sodium citrate Chemical Properties,Uses,Production
Description
Sodium citrate may refer to any of the sodium salts of citric acid (though most commonly the third):
Mono sodium citrate
Di sodium citrate
Tri sodium citrate
As food additives, the 3 forms of the salt are also collectively known by the E number E331.
Chemical Properties
Sodium citrate is odorless and has a pleasant, acid taste. Sodium citrate is anhydrous or contains two molecules of water of crystallization
Occurrence
Citric acid and its salts occur naturally in many plants and animals.
Uses
sodium citrate may be used in cosmetic formulations as an alkalizer and to bind trace metals in solutions (by means of a chelating action). It is the sodium salt of citric acid.
Preparation
Produced by the neutralization of citric acid with sodium hydroxide or sodium carbonate. May be prepared in an anhydrous state or may contain 2 mole of water per mole of sodium citrate.
Application
2 – 1 - Food
Sodium citrate is chiefly used as a food additive E331, usually for flavor or as a preservative. Sodium citrate is employed as a flavoring agent in certain varieties of club soda. Sodium citrate is common as an ingredient in Bratwurst, and is also used in commercial ready to drink beverages and drink mixes, contributing a tart flavour.
2 – 2 - Buffer
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH. Sodium citrate is used to control acidity in some substances, such as gelatin desserts. It can be found in the mini milk containers used with coffee machines. The compound is the product of antacids, such as Alka- Seltzer, when they are dissolved in water.
2 – 3 - Medical uses
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions. It continues to be used today in blood collection tubes and for the preservation of blood in blood banks. The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Sodium citrate is used to relieve discomfort in urinary tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. It is a major component of the WHO Oral Rehydration Solution.
General Description
Citric acid trisodium salt corresponds to a molecular weight of 258 Da. It has high sodium content and sieving coefficients.
Food additive
Sodium citrate is some times used as an acidity regulator in drinks, and also as an emulsifier for oils when making cheese. It allows the cheeses to melt with out becoming greasy. Consider the following quote from Modernist Cuisine:
Our modernist version of mac and cheese owes its chemistry to James L. Kraft, who in 1916 patented the first American cheese slice. He showed that sodium phosphate keeps the water and fat droplets mixed when the cheese is melted. We use sodium citrate, which has the same effect and is easier to find. The resulting texture is as smooth as melted American cheese, but as complex and intense in flavor as any of your favorite cheeses.
Purification Methods
Crystallise the salt from warm water by cooling to 0o. [Beilstein 3 III 1100, 3 IV 1274.]
Sodium citrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Rishi Chemical Works Pvt Ltd | +91-3322290068 +91-3322290071 | Kolkata, India | 43 | 58 | Inquiry |
| Yogi Dye Chem Industries | +91-9821098577 +91-9821098577 | Mumbai, India | 124 | 58 | Inquiry |
| Evans Fine Chem | +91-9821340302 +91-9821340302 | Maharashtra, India | 286 | 58 | Inquiry |
| Shreenath Chemicals | +91-8369634120 +91-8369634120 | Maharashtra, India | 48 | 58 | Inquiry |
| Choice Chemicals | +91-9895031268 +91-9895031268 | Kerela, India | 118 | 58 | Inquiry |
| SAANVI CORP | +91-7208939370 +91-7208939370 | Maharashtra, India | 46 | 58 | Inquiry |
| Medi Pharma Drug House | +919930911911 | Mumbai, India | 143 | 58 | Inquiry |
| AVA CHEMICALS PVT LTD | +91-8879390046 +91-8879390046 | Maharashtra, India | 74 | 58 | Inquiry |
| Kronox Lab Sciences Pvt Ltd | +91-9313231074 +91-9313231074 | Gujarat, India | 240 | 58 | Inquiry |
| India Phosphate | +91-9993319656 +91-9993319656 | Madhya Pradesh, India | 61 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Rishi Chemical Works Pvt Ltd | 58 |
| Yogi Dye Chem Industries | 58 |
| Evans Fine Chem | 58 |
| Shreenath Chemicals | 58 |
| Choice Chemicals | 58 |
| SAANVI CORP | 58 |
| Medi Pharma Drug House | 58 |
| AVA CHEMICALS PVT LTD | 58 |
| Kronox Lab Sciences Pvt Ltd | 58 |
| India Phosphate | 58 |
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