Tributyl citrate
- CAS No.
- 77-94-1
- Chemical Name:
- Tributyl citrate
- Synonyms
- Citroflex 4;BUTYL CITRATE;TRI-N-BUTYL CITRATE;nsc8491;citroflex4;Citroflex 4C;Tributylcitrat;N-BUTYLCITRATE;tributyl ester;TRIBUTYL CITRATE
- CBNumber:
- CB2299345
- Molecular Formula:
- C18H32O7
- Molecular Weight:
- 360.44
- MOL File:
- 77-94-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/13 18:00:15
| Melting point | ≥300 °C(lit.) |
|---|---|
| Boiling point | 234 °C (17 mmHg) |
| Density | 1.043 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | 300 °C |
| storage temp. | Store below +30°C. |
| solubility | Miscible with acetone, ethanol, and vegetable oil; practically insoluble in water. |
| pka | 11.30±0.29(Predicted) |
| form | Liquid |
| color | Clear |
| Odor | odorless |
| Water Solubility | insoluble |
| Merck | 14,1564 |
| BRN | 1806072 |
| InChIKey | ZFOZVQLOBQUTQQ-UHFFFAOYSA-N |
| LogP | 4.324 (est) |
| CAS DataBase Reference | 77-94-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Butyl citrate(77-94-1) |
| EPA Substance Registry System | 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tributyl ester (77-94-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 26-36/37/39-45-24/25 | |||||||||
| RIDADR | UN 2811 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TZ8608000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29181500 | |||||||||
| NFPA 704 |
|
Tributyl citrate price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.20350 | Tributyl citrate for synthesis | 77-94-1 | 100ML | ₹3490 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1154 | Tributyl citrate Pharmaceutical Secondary Standard; Certified Reference Material | 77-94-1 | 1G | ₹8270.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20350 | Tributyl citrate for synthesis | 77-94-1 | 1L | ₹10910 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 27497 | Tributyl citrate ≥97.0% | 77-94-1 | 100ML | ₹4968.68 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C0366 | Tributyl Citrate min. 98.0 % | 77-94-1 | 25ML | ₹1500 | 2022-05-26 | Buy |
Tributyl citrate Chemical Properties,Uses,Production
Chemical Properties
Tributyl citrate is a clear, odorless, practically colorless, oily liquid.
Uses
Tributyl Citrate, is a non-phthalate plasticizer, that can be used for the preparation of resins. It can also used for the synthesis of Acetyl Tributyl Cirate, a valuable biodegradable plasticizer of low toxicity, found in nail polish and other cosmetics.
Production Methods
Tributyl citrate is prepared by the esterification of citric acid with butanol.
General Description
Tributyl citrate is an ester of citric acid. It is used to plasticize polymers for coating solid drug dosage forms, tablets and capsules.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Pharmaceutical Applications
Tributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release, and enteric formulations.
Safety
Tributyl citrate is used in oral pharmaceutical formulations. It is
generally regarded as an essentially nontoxic and nonirritating
material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): >50 mL/kg
LD50 (mouse, IP): 2.9 g/kg
LD50 (rat, oral): >30 mL/kg
storage
Tributyl citrate should be stored in well-closed containers in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, tributyl citrate is a stable material.
Incompatibilities
Tributyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory Status
Approved in the USA for indirect food contact in food films. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Tributyl citrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SYNOVA CHEMICALS | +91-9920741772 +91-9920741772 | Mumbai, India | 428 | 58 | Inquiry |
| LANXESS India Pvt. Ltd. | +91-8356878763 +91-8356878763 | Maharashtra, India | 190 | 58 | Inquiry |
| Mruchem | +91-8087147166 +91-8087147166 | Gujarat, India | 52 | 58 | Inquiry |
| KLJ Group | +91-1141427427 +91-1145371400 | New Delhi, India | 29 | 58 | Inquiry |
| Lucknow Organics Pvt Ltd | +91-5224005505 +91-5224005505 | Uttar Pradesh, India | 8 | 58 | Inquiry |
| Nayakem Organics Pvt. Ltd | +91-022-24314854 +91-2224314854 | Maharashtra, India | 15 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| SYNOVA CHEMICALS | 58 |
| LANXESS India Pvt. Ltd. | 58 |
| Mruchem | 58 |
| KLJ Group | 58 |
| Lucknow Organics Pvt Ltd | 58 |
| Nayakem Organics Pvt. Ltd | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Central Drug House(P) Ltd. | 58 |