SOLASONINE
![SOLASONINE Structure](CAS/GIF/19121-58-5.gif)
- CAS No.
- 19121-58-5
- Chemical Name:
- SOLASONINE
- Synonyms
- SOLASONIN;PURAPURIN;NSC 82149;SOLANINE S;PURAPURINE;SOLASONINE;SOLANCARPIN;Solasoonine;SOLASODAMINE;α-Solasonine
- CBNumber:
- CB3274987
- Molecular Formula:
- C45H73NO16
- Molecular Weight:
- 884.07
- MOL File:
- 19121-58-5.mol
- Modify Date:
- 2023/8/24 17:20:48
SOLASONINE Chemical Properties,Uses,Production
Description
This gly<:oalkaloid occurs in several species of Solanum including S. aviculare, S. sodomeum, S. verbascifolium and S. xanthocarpum. The alkaloid crystallizes from 80 per cent EtOH with 4.5 H20, m.p. 245-250°C (dec.), the anhydrous form being obtained from absolute MeOH. It has [α]25D - 68° (EtOH) and yields the following salts: hydrochloride, m.p. 265°C; picrate, m.p. 199-201 °C; picrolonate, m.p. 230-loC and the acetyl derivative, m.p. l35-8°C. On alkaline hydrolysis, the alkaloid gives solasodine and one mole each of galactose, glucose and rhamnose. The solution in concentrated H2S04 eventually gives a crimson colour with a brown fluorescence.
Uses
α-Solasonine is a natural glycoalkaloid compound which has been shown to inhibit Gli-mediated transcritional activity.
Purification Methods
Solasonine crystallises from aqueous 80% dioxane or MeOH in needles. [Bell & Briggs J Chem Soc 1 1942, Briggs et al. J Chem Soc 4645 1961, Briggs et al. J Chem Soc 2848 1963.] The picrate crystallises from 30% aqueous EtOH with m 197-198o(dec) [Briggs & Cambie J Chem Soc 1422 1958]. [Beilstein 27 III/IV 2006.]
References
Oddo et a/., Gazzetta, 35, 27 (1905)
Levi., J. Soc. Chem. Ind., 49, 395T (1930)
Briggs., Nature, 144, 247 (1939)
Briggs.,J. Chem. Soc., 3 (1942)
Briggs, Vining., ibid, 2809 (1953)
Hayes, Scaforth., ibid, 74S (1963)
SOLASONINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 | China | 952 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 15093356674; | China | 29902 | 58 | Inquiry |
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Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |